Atopic dermatitis is a skin disorder characterized by intense itch, dry skin and redness. Often considered a benign disease, it actually impacts very negatively on quality of life, sometimes more than psoriasis and diabetes. Through opinion leader inte

While drug eluting stents have been successful in reducing the rate of restenosis following percutaneous coronary intervention, there have been safety scares over a new problem: "in-stent thrombosis". Opinion leaders are divided over the grav

Non-Hodgkin’s lymphoma (NHL) is the most common hematological malignancy and is comprised of around 30 different disease subtypes. Each of these present with a distinct set histological, genetic and clinical characteristics. Treatment options in

Mainly affecting women, fibromyalgia syndrome affects six million people in the US alone. This relatively common yet poorly understood syndrome is characterized by widespread muscle pain and fatigue and remains substantially underserved by the medical

Explores key issues in the development of biologics for infectious diseases. It identifies promising targets, highlights development difficulties and gives an overview of antibacterial, antiviral and antifungal pipeline projects.

Research and Development activity in the Hepatitis C arena continue to be high. The market still holds many areas of unmet medical needs: while existing therapies provide good efficacy for about half of the patient population, side effects and limited

An overview ofthe market for portable inhalers, looking at market shares,usefulness as tools for franchise protection and -expansion. Patient- and physician preferences are being analyzed as well as suitablility of molecules and inhaler types.

A meager 20% of metastatic RCC tumors respond to standard cytokine therapy, thus rendering 80% of advanced RCC patients without any effective treatment. Further, with up to 50% of stage one to three patients relapsing following nephrectomy and an incre

The global incidence of STIs is estimated at several hundreds of millions cases per year, and due to the asymptomatic nature of most infections, underreporting is likely to mask the real incidence. Most STIs can lead to severe sequelae, including infer

Idiopathic pulmonary fibrosis is a devastating, relentlessly progressive and lethal disease for which current therapy is minimally effective. However, several promising anti-fibrotic agents, such as Enbrel (etanercept), are now in clinical trials, whic

Recognizing that prolonging disease-free survival in chronic leukemia relies on the eradication of minimal residual disease has raised the bar for developers of novel pharmacotherapy. In meeting the more demanding success criteria and targeting innovat

The incidence of head and neck cancers is increasing. Surgery and radiation are employed with curative intent for early stage lesions. Chemotherapy concurrent with radiation and surgery is the treatment of choice for unresectable disease. The market is

The incidence of glioblastoma is increasing. Schering-Plough`s temozolomide has gained approval as first line therapy for glioblastoma and has provided some survival benefit. However, median survival is still a modest fifteen months. Thus, the glioblas

As in other areas of surgery, surgeons are looking to reduce the invasive nature of spinal surgery, in an attempt to improve patient outcomes. The potential benefits of minimally invasive spinal surgery such as microdiscectomy and mini spinal fusion in

The incidence of brain metastasis is escalating concurrent with improvements in systemic therapy increasing patient survival. There is no approved pharmacotherapy for these patients and current therapy is palliative. Median survival is four months. Thu

Headache is the most common complaint seen in family practice in the US, yet medical training gives little time to its diagnosis and treatment. Enabling improved diagnosis and an understanding of suitable treatment pathways for migraine will allow phar