This triple analysis focuses on cancer drug development strategies by mechanism/target/effect of Apoptosis, Cancer Vaccines and Protein Kinase Inhibitors. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.
Below is a short synopsis of each part included in this report:
Part I: Apoptosis
The apoptotic cancer drug report part comprises defined and up to date development strategies for 234 drugs in oncology within the portfolio of 158 companies world-wide, from Ceased to Marketed. The report extensively analyses their 181 identified drug targets, organized into 157 drug target strategies, and assesses them in 69 cancer indications.
This part is based on the following publication:
Commercializing Apoptotic Drugs in Cancer: The Faster Route to Consider Your Options and Position of Others
Part II: Cancer Vaccines
The cancer vaccine report part comprises defined and up to date development strategies for 155 cancer vaccine drugs within the portfolio of 99 investigators, from Ceased to Marketed. This part extensively analyses their 94 identified drug targets, organized into 91 drug target strategies, and assesses them in 42 different cancer indications.
This part is based on the following publication:
Commercializing Cancer Vaccines: A Decision Support Tool for Optimizing the Pipeline
Part III: Protein Kinase Inhibitors
The protein kinase drug report part comprises defined and up to date development strategies for 648 drugs in oncology within the portfolio of 212 companies world-wide, from Ceased to Marketed. The report extensively analyses their 183 identified drug targets, organized into 278 drug target strategies, and assesses them in 70 cancer indications.
This part is based on the following publication:
Competitive Insights to Protein Kinase Therapeutics in Oncology: The Faster Route to Consider Your Options and Position of Others
The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:
* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives
* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties
* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities
* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities
* Supporting development of integrative molecule, pathway and disease area strategies
* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment
This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.
Key Topics Covered:
Part I: Apoptosis
5.1 The Scope of this Report 33
6 Consider the Therapeutic Target Among Apoptotic Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (181 Drug Targets) 37-416
7 Emerging New Products to Established Ones: Drug Target Strategies of Apoptotic Drugs in Oncology by their Highest Stage of Development (157 Drug Target Strategies and 234 Drugs) 417-622
8 Compound Strategies at Work: Competitive Benchmarking of Apoptotic Cancer Drugs by Compound Strategy(7 Compound Strategies) 623-660
9 Selecting Indication for Apoptotic Drugs in Oncology (69 Cancer Indications) 661-776
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Apoptotic Drug Pipeline in Oncology by Investigator (158 Investigators and 234 Drugs) 777-1601
Disclaimer 1602
11 Drug Index 1603
12 Company Index 1611
Figures: Includes 7 Figures
Tables: Includes 315 Tables
Total Number of Pages: 1,617
Part II: Cancer Vaccines
5.1 The Scope of this Report 26
6 Consider the Therapeutic Target Among Cancer Vaccine Drugs for the Highest Therapeutic Outcome and Return on Investment (94 Drug Targets) 30-194
7 Emerging New Products to Established Ones: Drug Target Strategies of Cancer Vaccine Drugs by their Highest Stage of Development (91 Drug Target Strategies and 155 Cancer Vaccine Drugs) 195-308
8 Compound Strategies at Work: Competitive Benchmarking of Cancer Vaccine Drugs by Compound Strategy (7 Compound Strategies) 309-338
9 Selecting Cancer Indications for Cancer Vaccine Drugs (42 Cancer Indications) 339-386
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Cancer Vaccine Drug Pipeline by Investigator (99 Investigators) 387-649
11 Disclaimer 650
12 Drug Index 651
13 Company Index 656
Figures: Includes 6 Figures
Tables: Includes 205 Tables
Total Number of Pages: 659
Part III: Protein Kinase Inhibitors
5.1 The Scope of this Report 38
6 Consider the Therapeutic Target Among Protein Kinase Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (183 Drug Targets) 42-516
7 Emerging New Products to Established Ones: Drug Target Strategies of Protein Kinase Drugs in Oncology by their Highest Stage of Development (278 Drug Target Strategies and 648 Drugs) 517-945
8 Compound Strategies at Work: Competitive Benchmarking of Protein Kinase Cancer Drugs by Compound Strategy (8 Compound Strategies) 946-1013
9 Selecting Indication for Protein Kinase Drugs in Oncology (70 Cancer Indications) 1014-1223
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Protein Kinase Drug Pipeline in Oncology by Investigator (212 Investigators and 648 Drugs) 1224-2939
11 Disclaimer 2940
Figures: Includes 8 Figures
Tables: Includes 389 Tables
Total Number of Pages: 2,940
4SC
AB Science
Abbott
Abiogen
AC Immune
Acceleron Pharma
Access
ACT Biotech
Adaptimmune
Aduro BioTech
Advanced Life Sciences
Advaxis
Advenchen
AEgera
AEterna Zentaris
Aida Pharmaceuticals
Aileron Therapeutics
Akela Pharma
Alethia Biotherapeutics
Allist Pharmaceuticals
Allostera
Alnylam
AlphaVax
Ambit Biosciences
Ambrilia Biopharma
Amgen
Amphora
Anadys Pharmaceuticals
Anaphore
Anavex Life Sciences
Ansaris
Antisoma
Aphios
Apogee Biotechnology
Apogenix
ApopLogic Pharmaceuticals
Apthera
Ariad
Arno Therapeutics
ArQule
Array BioPharma
Ascenta Therapeutics
Astellas
Astex Pharmaceuticals
Astex Therapeutics
AstraZeneca
Attenuon
AVI BioPharma
Avila Therapeutics
Basilea Pharmaceutica
Bavarian Nordic
Bayer
Bellicum Pharmaceuticals
Benitec
Berkeley Lab
Bio-Path Holdings
BioAlliance Pharma
BioAxone
Biocad
Biogen Idec
BioInvent
BioLineRx
Biomas
Bionovo
Biostar
Biotecnol
Biotica Technology
BioVex
Boehringer Ingelheim
Bristol-Myers Squibb
BTG
Cadila
Callisto Pharmaceuticals
Cambrex
CanBas
Cancer Research Technology
Catalyst Biosciences
CDG Therapeutics
Celera
Celgene
Cell Genesys
Cell Therapeutics
CellCeutix
Celldex Therapeutics
Celleron
Cephalon
CerRx
CG Therapeutics
ChemoCentryx
Chlorogen
Chroma Therapeutics
Circadian Technologies
Cleveland BioLabs
Clinical Data
CombinatoRx
CompleGen
Compugen
CoNCERT Pharmaceuticals
Coronado Biosciences
Cosmo Pharmaceuticals
Critical Outcome Technologies
CSL
Curis
Cyclacel
Cylene Pharmaceuticals
Cynvec
CytImmune Sciences
Cytochroma
Cytokine PharmaSciences
Cytopia
CytRx
Daewoong
Daiichi Sankyo
Dainippon Sumitomo Pharma
Debiopharm
Deciphera Pharmaceuticals
Dendreon
DeveloGen
DiaMedica
Dyax
Eisai
Elara Pharmaceuticals
Eleos
Eli Lilly
Emergent BioSolutions
Enkam Pharmaceuticals
EntreMed
Enzon
Epeius Biotechnologies
EpiCept
Erimos
Exelixis
Galapagos
Galena Biopharma
Generex
GenOdyssee Pharmaceuticals
Genta
GENTICEL
Gerolymatos
Geron
Gilead Sciences
GlaxoSmithKline
Gliknik
GlobeImmune
GlycoGenesys
Glycotope
GPC Biotech
Gradalis
Green Cross
Hanmi
Harbor BioSciences
Hoffmann-La Roche
Human Genome Sciences
Hutchison China MediTech
Hypha Discovery
Ichor Medical Systems
Idera Pharmaceuticals
ImClone Systems
ImmunoCellular Therapeutics
ImmunoFrontier
Immunotope
Incozen Therapeutics
Incyte Corporation
Infinity Pharmaceuticals
Inhibiton Therapeutics
Innate Pharma
InNexus Biotechnology
Inovio
Insmed
Insys Therapeutics
Intellikine
Intradigm
Introgen Therapeutics
ISA Pharmaceuticals
Isis Pharmaceuticals
ISU ABXIS
Jina Pharmaceuticals
Johnson & Johnson
Kadmon
KAI Pharmaceuticals
KaloBios
Kalypsys
Karus Therapeutics
Keryx Biopharmaceuticals
Kiadis
Kinex
Kirin Pharma
KuDOS
Kyowa Hakko Kirin
Leo
Lexicon Pharmaceuticals
Ligand
Lorus Therapeutics
Marina Biotech
MaxoCore Pharmaceuticals
Meda
Medical Marketing International
MediGene
Medisyn Technologies
Menarini
Merck & Co
Merck KGaA
Merrimack
MethylGene
Micromet
Mitsubishi Tanabe Pharma
Molecular LogiX
MolMed
Mologen
Myrexis
Nano Terra
Nemod Biotherapeutics
Neovacs
Nereus Pharmaceuticals
Nerviano Medical Sciences
NexusPharma
NicOx
Nidus Laboratories
NIH
Nippon Shinyaku
Non-industrial source
Northwest Biotherapeutics
Novacea
NovaLead
Novartis
NovaRx
Novelix
Novogen
Oncalis
OncoMune
Onconova
OncoTherapy Science
Oncothyreon
Oncovir
Onyvax
OSI Pharmaceuticals
Oxford BioMedica
OXiGENE
PanaGin
Pathway Therapeutics
Patrys
Pepscan Systems
Pepscan Therapeutics
Peregrine Pharmaceuticals
Pfizer
Pharmacyclics
PharmaGap
PharmaMar
Pharmexa
Pharminox
Phoenix Biotechnology
PHusis Therapeutics
Pieris
Pierre Fabre
Piramal
PIramed
Portola Pharmaceuticals
Prima Biomed
Proacta
Progenics Pharmaceuticals
ProMetic Life Sciences
Protherics
Provid
QLT
Quantum Pharmaceuticals
Radient Pharmaceuticals
Ras Therapeutics
Reata Pharmaceuticals
Receptor BioLogix
Regulon
responsif
Rexahn
Rigel
Rosetta Genomics
Samtheo Biopharma
Sanofi
Sanofi-Aventis
Santaris Pharma
Sareum
SBI Biotech
SBIO
Scancell
Schering-Plough
SciClone Pharmaceuticals
Seattle Genetics
Selvita
Semafore Pharmaceuticals
Senesco Technologies
Sentinel Oncology
SGX Pharmaceuticals
Sigma-Tau
Silence Therapeutics
SRI International
Sunesis
SuperGen
Supratek Pharma
Swedish Orphan Biovitrum
Switch Pharma
SymBio Pharmaceuticals
Symbiotec
Symphogen
Takeda
Tamir Biotechnology
TapImmune
Targa Therapeutics
TargeGen
TauTaTis
Taxolog
TCD Pharma
Tekmira Pharmaceuticals
Telik
TetraLogic Pharmaceuticals
Teva
Thallion Pharmaceuticals
Therion Biologics
Theryte
Tigris Pharmaceuticals
ToolGen
TopoTarget
Tracon Pharmaceuticals
Tragara Pharmaceuticals
Transgene
TransTech Pharma
UCB
UMN Pharma
United Biomedical
Vaccinex
ValiRx
VasGene Therapeutics
Vaxil BioTherapeutics
Vaxon Biotech
VaxOnco
VBL Therapeutics
Vectura
Velacor Therapeutics
Vernalis
Vertex Pharmaceuticals
Vical
VioQuest
Viragen
Viralytics
Virionics
ViroMed
ViroTarg
VM Discovery
Wyeth
Xcovery
Xencor
YM BioSciences
Zensun
Zenyaku Kogyo
131I-tositumomab
AC-480
ADXS11-001
AE-37
AEG-35156
AF-802
afatinib
ALVAC-CEA/B7.1
alvocidib
AME-133
AMG-386
Angiozyme
apatinib
APG-101
AR-42
ARQ-197
AS-101
AS-1411
astuprotimut-r
AT-7519
AT-9283
AVX-701
axitinib
AZD-8055
AZD-8931
bafetinib
barasertib
bardoxolone methyl
belagenpumatucel-L
belinostat
BEZ-235
BGT-226
BI-811283
BIBF-1120
BMS-690514
BMS-754807
BMS-777607
bortezomib
bosutinib
BP-GMAX-CD1
brivanib alaninate
BZL-101
Cabozantinib
Cadi-05
CAL-101
canfosfamide hydrochloride
CB-10-01
CBP-501
CC-223
CEA-TRICOM
cediranib
cenersen
CG-201
cintredekin besudotox
CMLVAX-100
conatumumab
crizotinib
crolibulin
CTL901
CTP-37
CVac
dacomitinib
danusertib
dasatinib
DCVax-prostate
dinaciclib
dovitinib lactate
dulanermin
E-75
endoxifen
ENMD-2076
enzastaurin hydrochloride
erlotinib
everolimus
foretinib
fosbretabulin tromethamine
fostamatinib disodium
fowlpox-PSA vaccine
gataparsen
gefitinib
GRNVAC1
GSK-2118436
GT-111
GV-1001
GV-1002
GVAX
GVX-3322
HE-3235
Her-2/Neu peptides
ibritumomab tiuxetan
IC-83
icrucumab
idronoxil
IGN-101
imatinib mesilate
imetelstat
ImmunoVEX tri-melan
IMO-2055
INCB-028060
INGN-225
INSM-18
JI-101
kahalalide F
KD032
KX2-391
lapatinib ditosylate
lenvatinib
lestaurtinib
linifanib
linsitinib
litronesib
lonaprisan
lumiliximab
LY-2090314
MAGE-3-TK
mapatumumab
masitinib
ME-103
MGCD-265
MGN-1601
midostaurin
MK-1775
MKC-1
MLN-8237
MM-111
mocetinostat
motesanib diphosphate
motexafin gadolinium
MSI vaccine
MVA-BN
MVA-BN Her-2 vaccine
navitoclax
neratinib
nilotinib
Norelin
noscapine
NPB-001-056
obinutuzumab
oblimersen sodium
ON-01910
onartuzumab
Oncohist
Onyvax-105
OSI-027
OTS-102
P276-00
panobinostat
PANVAC-VF
PAT-SC1
pazopanib hydrochloride
PBI-1402
PCI-24781
PD-0332991
pDOM-PSMA27
pegdinetanib
PEP-223
perifosine
PHA-848125AC
plitidepsin
poly-ICLC
ponatinib
PR1:169-177 peptide
PROSTVAC
PX-104.1
PX-12
PX-866
quarfloxacin
quinacrine
quizartinib dihydrochloride
R-(-)-gossypol
RAF-265
ramucirumab
regorafenib
retaspimycin
Reximmune-C
ridaforolimus
rilotumumab
rindopepimut
ruxolitinib
RX-0201-N
sagopilone
SAI-EGF
SCH-900776
seliciclib
sirolimus
sorafenib tosylate
SPC-2996
ß-lapachone
Stimuvax
SU-6668
sunitinib malate
talmapimod
tandutinib
telatinib
temsirolimus
terameprocol
TG-4001
TG-4010
thymalfasin
tigapotide triflutate
tigatuzumab
tipifarnib
tivozanib
TL-32711
triciribine phosphate
TroVax
TRU-016
vandetanib
varlitinib
vemurafenib
verpasep caltespen
volasertib
vosaroxin
VX-001
XL-147
XL-281
XL-413
XL-647
XL-765
ZYC-300
Other selected research from the 'Triple Analysis' category:
Triple Analysis: Leukemia, Prostate Cancer and Peptides
Triple Analysis: Breast Cancer, Lung Cancer and Prostate Cancer
Other selected research from the 'Oncology' category:
Triple Analysis: Colorectal Cancer, Lung Cancer and Lymphoma
Innovations in Cancer: Novel therapeutics, new diagnostics and future R&D strategies
