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Triple Analysis: Apoptosis, Protein Kinase Inhibitors and Antibodies

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Published Date Dec 19, 2011
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Find the Triple Analysis Report in oncology which best suits your needs by selecting any three (3) out of these 14 high impact Cancer Focus Areas.

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Quick Overview

This triple analysis focuses on cancer drug development strategies by the two mechanism/target/effect areas of Apoptosis and Protein Kinase Inhibitors and by the compound strategy of Antibodies.
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This triple analysis focuses on cancer drug development strategies by the two mechanism/target/effect areas of Apoptosis and Protein Kinase Inhibitors and by the compound strategy of Antibodies. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.

Below is a short synopsis of each part included in this report:

Part I: Apoptosis
The apoptotic cancer drug report part comprises defined and up to date development strategies for 234 drugs in oncology within the portfolio of 158 companies world-wide, from Ceased to Marketed. The report extensively analyses their 181 identified drug targets, organized into 157 drug target strategies, and assesses them in 69 cancer indications.
This part is based on the following publication:
Commercializing Apoptotic Drugs in Cancer: The Faster Route to Consider Your Options and Position of Others

Part II: Protein Kinase Inhibitors
The protein kinase report comprises defined and up to date development strategies for 409 protein kinase drugs (990 projects) within the portfolio of 160 investigators, from Ceased to Marketed. This report part extensively analyses 133 identified targets of protein kinase drugs, organized into 200 drug target strategies, and assesses them in 57 different cancer indications.
This part is based on the following publication:
Protein Kinase Therapeutics in Oncology - Where to Commercialize?

Part III: Antibodies
The cancer antibody drug report part comprises defined and up to date development strategies for 531 antibody drugs in oncology within the portfolio of 196 companies world-wide, from Ceased to Marketed. The report extensively analyses their 255 identified drug targets, organized into 266 drug target strategies, and assesses them in 75 cancer indications.
This part is based on the following publication:
The Global Competitive Landscape of Antibody Drug Development in Cancer: The Faster Route to Consider Your Options and Position of Others

The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:

* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives

* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties

* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities

* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities

* Supporting development of integrative molecule, pathway and disease area strategies

* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment

This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.

Key Topics Covered:

Part I: Apoptosis
5.1 The Scope of this Report 33
6 Consider the Therapeutic Target Among Apoptotic Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (181 Drug Targets) 37-416
7 Emerging New Products to Established Ones: Drug Target Strategies of Apoptotic Drugs in Oncology by their Highest Stage of Development (157 Drug Target Strategies and 234 Drugs) 417-622
8 Compound Strategies at Work: Competitive Benchmarking of Apoptotic Cancer Drugs by Compound Strategy(7 Compound Strategies) 623-660
9 Selecting Indication for Apoptotic Drugs in Oncology (69 Cancer Indications) 661-776
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Apoptotic Drug Pipeline in Oncology by Investigator (158 Investigators and 234 Drugs) 777-1601
Disclaimer 1602
11 Drug Index 1603
12 Company Index 1611
Figures: Includes 7 Figures
Tables: Includes 315 Tables
Total Number of Pages: 1,617

Part II: Protein Kinase Inhibitors
5.1 The Scope of this Report 30
6 Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (133 Drug Targets) 36-336
7 The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Profiles Identified in the Cancer Protein Kinase Therapeutic Pipeline? (200 Drug Target Strategies and 409 Drugs) 337-407
8 Compound Strategies at Work: Competitive Benchmarking of Protein Kinase Drugs in Oncology by Compound Type (7 Compound Strategies) 408-495
9 Selecting Cancer Indications for Protein Kinase Therapeutics (57 Different Cancer Indications) 496-649
10 Portfolio Planning: Competitive Benchmarking of Protein Kinase Cancer Therapeutic Pipeline by Investigator (160 Investigators) 650-1417
12 Drug Index 1419
13 Company Index 1433
Figures: Includes 6 Figures
Tables: Includes 302 Tables
Total Number of Pages: 1442

Part III: Antibodies
5.1 The Scope of this Report 35
6 Consider the Therapeutic Target Among Antibody Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (255 Drug Targets) 39-430
7 Emerging New Products to Established Ones: Drug Target Strategies of Antibody Drugs in Oncology by their Highest Stage of Development (266 Drug Targets Strategies and 531 Antibody Drugs) 431-768
8 Selecting Cancer Indication for Antibody Drugs (75 Cancer Indications) 769-893
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Antibody Drug Pipeline in Oncology by Investigator (196 Investigators and 531 Antibody Drugs) 894-1,916
10 Disclaimer 1917
11 Drug Index 1918
12 Company Index 1934
Figures: Includes 5 Figures
Tables: Includes 347 Tables
Total Number of Pages: 1,944

This Report Includes the Following Companies:
4SC
A&G Pharmaceutical
Abbott
Abiogen
Ablynx
Abraxis BioScience
AC Immune
Acceleron Pharma
Access
Actinium Pharmaceuticals
Active Biotech
Adherex
Advanced Life Sciences
Advenchen
AEgera
AEterna Zentaris
Affibody
Affimed Therapeutics
Affitech
AGY Therapeutics
Aida Pharmaceuticals
Aileron Therapeutics
Alder Biopharmaceuticals
Alethia Biotherapeutics
Alexion
Alfacell
Algeta
Alnylam
AlphaVax
ALSP
Altor BioScience
Ambit Biosciences
Ambrilia Biopharma
Amgen
Amorfix Life Sciences
Amphora
Anadys Pharmaceuticals
Anaphore
Anavex Life Sciences
Antisoma
Aphios
Apogenix
ApopLogic Pharmaceuticals
Apricus Biosciences
Apthera
Arana Therapeutics
Arca biopharma
arGEN-X
Ariad
Arno Therapeutics
ArQule
Array BioPharma
Ascenta Therapeutics
Astellas
Astex Therapeutics
AstraZeneca
Attenuon
Avaxia
AVEO
Avila Therapeutics
Basilea Pharmaceutica
Bayer
Benitec
Berkeley Lab
BioAlliance Pharma
BioAxone
Biocad
Biocon
Biogen Idec
BioInvent
Biolex
BioLineRx
Biomas
Bionovo
Biosceptre
Biotecnol
Biotest
BioVex
Boehringer Ingelheim
Bristol-Myers Squibb
BTG
Callisto Pharmaceuticals
CanBas
Cancer Innovations
Cancer Research Technology
CDG Therapeutics
Celera
Celgene
Cell Therapeutics
Celldex Therapeutics
Celltrion
Celtic Pharma
Center of Molecular Immunology
Cephalon
CG Therapeutics
ChemoCentryx
Chlorogen
Chroma Therapeutics
Circadian Technologies
Cleveland BioLabs
CombinatoRx
CompleGen
Compugen
Coronado Biosciences
Critical Outcome Technologies
CSL
CuraGen
CureTech
Curis
Cyclacel
Cylene Pharmaceuticals
Cynvec
CytImmune Sciences
Cytochroma
CytRx
Daewoong
Daiichi Sankyo
Dainippon Sumitomo Pharma
Deciphera Pharmaceuticals
Dendreon
DeveloGen
DiaMedica
Dompe
Dr Reddy’s
Dyax
Eisai
Elan
Elara Pharmaceuticals
Eleos
Eli Lilly
Emergent BioSolutions
Enkam Pharmaceuticals
EntreMed
EpiCept
Epitomics
Erimos
EUSA Pharma
Exelixis
Faron Pharmaceuticals
Favrille
Femta Pharmaceuticals
FibroGen
Five Prime Therapeutics
Fusion Antibodies
Galapagos
Galaxy Biotech
GammaCan
Ganymed Pharmaceuticals
Gene Techno Science
Genencor
Genentech
Generex
Genmab
Genomic Systems
GenPat77
Genta
Gerolymatos
Geron
Gilead Sciences
GlaxoSmithKline
Gliknik
GlycoGenesys
Glycotope
GPC Biotech
Green Cross
Hanmi
Harbor BioSciences
Hawthorn Pharmaceuticals
Hoffmann-La Roche
Human Genome Sciences
Idera Pharmaceuticals
IDM Pharma
ImClone Systems
IMED
Immune Pharmaceuticals
ImmunoCellular Therapeutics
ImmunoFrontier
ImmunoGen
Immunomedics
Immutep
Incyte Corporation
Infinity Pharmaceuticals
Innate Pharma
InNexus Biotechnology
Inovio
Insmed
Insys Therapeutics
Intracel
Intradigm
Introgen Therapeutics
ISA Pharmaceuticals
Isis Pharmaceuticals
ISU ABXIS
Johnson & Johnson
KAI Pharmaceuticals
Kaketsuken
KaloBios
Kalypsys
Keryx Biopharmaceuticals
Kiadis
Kirin Pharma
Kissei
Kyowa Hakko Kirin
Kyto Biopharma
Leo
LFB Biotechnologies
LG Life Sciences
Ligand
Locus Pharmaceuticals
Lorus Therapeutics
MacroGenics
MAT Biopharma
MaxoCore Pharmaceuticals
Medarex
MediGene
MedImmune
Medisyn Technologies
Menarini
Merck & Co
Merck KGaA
Merrimack
MethylGene
Micromet
Mitsubishi Tanabe Pharma
Mycenax
NeoPharm
Neovacs
Nereus Pharmaceuticals
Nerviano Medical Sciences
Neuren
NicOx
Nidus Laboratories
NIH
Nippon Shinyaku
NKT Therapeutics
Non-industrial source
Northwest Biotherapeutics
Novacea
NovaLead
Novartis
Novelix
Novogen
Oncalis
OncoMed
Onconova
OncoTherapy Science
Oncothyreon
Onyvax
OSI Pharmaceuticals
Oxford BioMedica
OXiGENE
Paladin Labs
Panacea
PanaGin
PanGenetics
Patrys
Pepscan Therapeutics
Peregrine Pharmaceuticals
Perseus Proteomics
Pfizer
Pharmacyclics
PharmaGap
PharmaMar
Pharmexa
Pharminox
Philogen
Pierre Fabre
Piramal
Plexxikon
Prima Biomed
ProCell Therapeutics
Prochon Biotech
Progenics Pharmaceuticals
ProMetic Life Sciences
QLT
Ramot
Reata Pharmaceuticals
Recepta biopharma
Receptor BioLogix
Regeneron
Regulon
Rexahn
Rigel
Rosetta Genomics
Sanofi
Sanofi-Aventis
Santaris Pharma
Sareum
SBI Biotech
SBIO
Scancell
Schering-Plough
Seattle Genetics
Semafore Pharmaceuticals
Senesco Technologies
Shenogen
Sigma-Tau
Silence Therapeutics
SRI International
Stainwei Biotech
Sunol Molecular
SuperGen
SuppreMol
Supratek Pharma
Switch Pharma
SymBio Pharmaceuticals
Symbiotec
Symphogen
Synageva BioPharma
SynerGene Therapeutics
Takeda
Targa Therapeutics
TargeGen
Taxolog
TeGenero
Tekmira Pharmaceuticals
Telik
TetraLogic Pharmaceuticals
Teva
Thallion Pharmaceuticals
Therapure Biopharma
Theryte
ThromboGenics
Tigris Pharmaceuticals
Titan Pharmaceuticals
Tolerx
ToolGen
TopoTarget
Tracon Pharmaceuticals
Transgene
Trillium Therapeutics
Trion Pharma
UCB
UMN Pharma
United Therapeutics
Vaccinex
Wakunaga
ValiRx
VasGene Therapeutics
VBL Therapeutics
Velacor Therapeutics
Vertex Pharmaceuticals
Vical
Wilex
VioQuest
Viragen
Viralytics
ViroMed
ViroTarg
Viventia Biotech
VM Discovery
Wyeth
XBiotech
Xencor
Xerion
Xoma
Y’s Therapeutics
YM BioSciences
Zenotech
A Shortlist of Drugs Included are:
131I-tositumomab
abagovomab
AEG-35156
aflibercept
alemtuzumab
alvocidib
AME-133
AMG-386
APG-101
ARQ-197
AS-101
AS-1411
axitinib
bardoxolone methyl
belinostat
bevacizumab
BIBW-2992
bortezomib
bosutinib
brentuximab vedotin
brivanib alaninate
BZL-101
canfosfamide hydrochloride
catumaxomab
cediranib
cenersen
cetuximab
cintredekin besudotox
conatumumab
crolibulin
dasatinib
deforolimus
denosumab
dinaciclib
dulanermin
E-75
enzastaurin hydrochloride
erlotinib
everolimus
farletuzumab
fosbretabulin tromethamine
galiximab
gataparsen
gefitinib
gemtuzumab ozogamicin
girentuximab
GT-111
HE-3235
ibritumomab tiuxetan
idronoxil
imatinib mesilate
imetelstat
inotuzumab ozogamicin
ipilimumab
kahalalide F
lapatinib ditosylate
lestaurtinib
litronesib
lonaprisan
lumiliximab
mapatumumab
midostaurin
MKC-1
mocetinostat
motesanib diphosphate
motexafin gadolinium
naptumomab estafenatox
navitoclax
necitumumab
nilotinib
nimotuzumab
noscapine
obinutuzumab
oblimersen sodium
ofatumumab
ON-01910
Oncohist
oregovomab
panitumumab
panobinostat
PAT-SC1
pazopanib hydrochloride
PBI-1402
PCI-24781
pertuzumab
plitidepsin
PX-12
quarfloxacin
quinacrine
R-(-)-gossypol
RAF-265
ramucirumab
Reditux
retaspimycin
rituximab
sagopilone
seliciclib
sorafenib tosylate
SPC-2996
ß-lapachone
SU-6668
sunitinib malate
tanespimycin
temsirolimus
terameprocol
tigapotide triflutate
tigatuzumab
tipifarnib
TL-32711
trastuzumab
triciribine phosphate
TRU-016
vandetanib
volasertib
vosaroxin
XL-147
XL-184
XL-647
zalutumumab
zanolimumab
Request free sample pages from Triple Analysis: Apoptosis, Protein Kinase Inhibitors and Antibodies

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