This triple analysis focuses on cancer drug development strategies in Breast Cancer and by the two mechanism/target/effect areas of Apoptosis and Angiogenesis. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.
Below is a short synopsis of each part included in this report:
Part I: Breast Cancer
The breast cancer report part comprises defined and up to date development strategies for 405 breast cancer drugs within the portfolio of 220 investigators, from Ceased to Marketed. This report part extensively analyses 207 identified targets of breast cancer drugs, organized into 193 drug target strategies, and assesses them in breast cancer.
This part is based on the following publication:
Portfolio Analytics and Planning in the Breast Cancer Pipeline - Change is Around the Corner in a Highly Competitive Market Place
Part II: Apoptosis
The apoptotic cancer drug report part comprises defined and up to date development strategies for 234 drugs in oncology within the portfolio of 158 companies world-wide, from Ceased to Marketed. The report extensively analyses their 181 identified drug targets, organized into 157 drug target strategies, and assesses them in 69 cancer indications.
This part is based on the following publication:
Commercializing Apoptotic Drugs in Cancer: The Faster Route to Consider Your Options and Position of Others
Part III: Angiogenesis
The angiogenesis report part comprises defined and up to date development strategies for 239 drugs affecting angiogenesis in oncology within the portfolio of 148 investigators, from Preclinical to Marketed. This report part extensively analyses 174 identified targets of angiogenesis affecting drugs, organized into 167 drug target strategies, and assesses them in 64 different cancer indications.
This part is based on the following publication:
Commercializing Cancer Drugs Affecting Angiogenesis: A Decision Support Tool for Optimizing the Pipeline
The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:
* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives
* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties
* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities
* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities
* Supporting development of integrative molecule, pathway and disease area strategies
* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment
This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.
Key Topics Covered:
Part I: Breast Cancer
5.1 The Scope of this Report 29
6 Consider the Therapeutic Breast Cancer Target for the Highest Therapeutic Outcome and Return on Investment (207 Drug Targets) 33-376
7 The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Strategies Identified in the Breast Cancer Therapeutic Pipeline? (193 Drug Target Strategies and 405 Drugs) 377-441
8 Compound Strategies at Work: Competitive Benchmarking of Breast Cancer Drugs by Compound Strategy (8 Different Compound Strategies) 442-488
9 Pipeline and Portfolio Planning: Competitive Benchmarking of Breast Cancer Therapeutic Pipeline by Investigator (220 Investigators) 489-891
11 Drug Index 893
12 Company Index 905
Figures: Includes 7 Figures
Tables: Includes 274 Tables
Total Number of Pages: 913
Part II: Apoptosis
5.1 The Scope of this Report 33
6 Consider the Therapeutic Target Among Apoptotic Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (181 Drug Targets) 37-416
7 Emerging New Products to Established Ones: Drug Target Strategies of Apoptotic Drugs in Oncology by their Highest Stage of Development (157 Drug Target Strategies and 234 Drugs) 417-622
8 Compound Strategies at Work: Competitive Benchmarking of Apoptotic Cancer Drugs by Compound Strategy(7 Compound Strategies) 623-660
9 Selecting Indication for Apoptotic Drugs in Oncology (69 Cancer Indications) 661-776
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Apoptotic Drug Pipeline in Oncology by Investigator (158 Investigators and 234 Drugs) 777-1601
Disclaimer 1602
11 Drug Index 1603
12 Company Index 1611
Figures: Includes 7 Figures
Tables: Includes 315 Tables
Total Number of Pages: 1,617
Part III: Angiogenesis
5.1 The Scope of this Report 35
6 Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (174 Drug Targets) 39-366
7 Emerging New Products to Established Ones: Drug Target Strategies of Cancer Drugs Affecting Angiogenesis by their Highest Stage of Development (167 Drug Target Strategies and 239 Drugs) 367-437
8 Compound Strategies at Work: Competitive Benchmarking of Cancer Drugs Affecting Angiogenesis by Compound Strategy (7 Different Compound Strategies) 438-485
9 Selecting Cancer Indications for Angiogenesis Affecting Drugs in Oncology (64 Cancer Indications) 486-643
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Angiogenesis Affecting Drug Pipeline in Oncology by Investigator (148 Investigators) 644-1211
10 Disclaimer 1212
11 Drug Index 1213
12 Company Index 1221
Figures: Includes 7 Figures
Tables: Includes 300 Tables
Total Number of Pages: 1227
A&G Pharmaceutical
Abbott
Abiogen
Abraxis BioScience
Acceleron Pharma
Access
ACT Biotech
Active Biotech
Adherex
Advanced Cancer Therapeutics
Advanced Life Sciences
Advantagene
Advaxis
Advenchen
AEgera
AEterna Zentaris
Affibody
Agennix
Aida Pharmaceuticals
Aileron Therapeutics
Alchemia
Alethia Biotherapeutics
Alnis Biosciences
Alnylam
AlphaVax
Alseres Pharmaceuticals
Ambit Biosciences
Ambrilia Biopharma
Amgen
Amphora
Anadys Pharmaceuticals
Anaphore
Anavex Life Sciences
AngioChem
Angiogen
Angiogenex
Angstrom Pharmaceuticals
Ansaris
Antisoma
Aphios
Apogenix
ApopLogic Pharmaceuticals
Apthera
Arana Therapeutics
Archer Biosciences
Ariad
Arno Therapeutics
ArQule
Array BioPharma
Ascend Therapeutics
Ascenta Therapeutics
Astellas
Astex Therapeutics
AstraZeneca
Attenuon
Austrianova
AVI BioPharma
Avila Therapeutics
Basilea Pharmaceutica
Bavarian Nordic
Bayer
Betagenon
BioAlliance Pharma
BioAxone
Biocad
Biocompatibles
Biogen Idec
BioInvent
BioLineRx
Biomas
Bionovo
BioVex
Boehringer Ingelheim
Bolder BioTechnology
Bristol-Myers Squibb
BTG
Callisto Pharmaceuticals
Cancer Research Technology
CDG Therapeutics
Cel-Sci
Celecure
Celera
Celgene
Cell Genesys
Cell Therapeutics
CellCeutix
Celldex Therapeutics
Cellmid
Celsion
Celtic Pharma
Center of Molecular Immunology
Cephalon
ChemGenex Pharmaceuticals
ChemoCentryx
Chemokine Therapeutics
Chiesi
China Sky One Medical
Chlorogen
Choongwae
Chroma Therapeutics
Circadian Technologies
Cleveland BioLabs
CombinatoRx
CompleGen
Coronado Biosciences
Critical Outcome Technologies
Cue Biotech
Curis
Cyclacel
Cylene Pharmaceuticals
Cynvec
CytImmune Sciences
Cytochroma
Cytokinetics
CytRx
Daewoong
Daiichi Sankyo
Dainippon Sumitomo Pharma
Debiopharm
Deciphera Pharmaceuticals
Dendreon
DeveloGen
Dong-A
Dongkook Pharm
Douglas
Dyax
ECI
Eisai
Elan
Elara Pharmaceuticals
Eleos
Eli Lilly
Emergent BioSolutions
Endoceutics
Endocyte
Enkam Pharmaceuticals
EntreMed
Enzon
Epeius Biotechnologies
EpiCept
Erimos
Eucodis
Exelixis
ExonHit Therapeutics
Facet Biotech
Five Prime Therapeutics
Fresenius
GammaCan
Genentech
Generex
Genmab
Genta
GenVec
Genzyme
Gerolymatos
Geron
GlaxoSmithKline
Gloucester Pharmaceuticals
GlycoGenesys
Glycotope
GlyTag
Got-a-Gene
GPC Biotech
Green Cross
Harbor BioSciences
Heidelberg Pharma
Hoffmann-La Roche
Hospira
Human Genome Sciences
Hy BioPharma
Idera Pharmaceuticals
ImClone Systems
Immunocore
ImmunoGen
Immunomedics
Immunotope
ImmuPharma
Immutep
Incyte Corporation
Inex
Infinity Pharmaceuticals
Innate Pharma
InNexus Biotechnology
Inovio
Insmed
Insys Therapeutics
Intarcia Therapeutics
Intezyne Technologies
Intradigm
Introgen Therapeutics
Ipsen
Isis Pharmaceuticals
ISU ABXIS
Johnson & Johnson
KAI Pharmaceuticals
Kalypsys
Karus Therapeutics
Keryx Biopharmaceuticals
Kiadis
Kirin Pharma
Kringle Pharma
Kyowa Hakko Kirin
LEAD Therapeutics
Lee’s Pharmaceutical
Leo
Ligand
Lorus Therapeutics
Marillion Pharmaceuticals
MAT Biopharma
MDRNA
Meda
Medarex
MediGene
MedImmune
Mediolanum
Medisyn Technologies
Meiji
Menarini
Merck & Co
Merck KGaA
Mersana Therapeutics
MethylGene
Micromet
MolMed
Mologen
Morvus Technology
NanoMed Pharmaceuticals
Nektar Therapeutics
Nemod Biotherapeutics
NeoPharm
Nereus Pharmaceuticals
Nerviano Medical Sciences
NewSouth Innovations
NexGenix Pharmaceuticals
Nidus Laboratories
NIH
Nippon Kayaku
Nippon Shinyaku
Non-industrial source
Novacea
NovaLead
Novartis
Novelix
Novogen
Oasmia
OncoGenex Pharmaceuticals
OncoMune
Onconova
OncoTherapy Science
Oncothyreon
Orion Pharma
OSI Pharmaceuticals
Oxford BioMedica
OXiGENE
Paladin Labs
PanaGin
Pantarhei Bioscience
Patrys
Pepscan Therapeutics
PepTcell
PepTx
Peregrine Pharmaceuticals
Pfizer
Pharmacopeia
Pharmacyclics
PharmaGap
PharmaMar
Pharmexa
Pharminox
PheneX
Philogen
PhiloGene
Pierre Fabre
Plexxikon
Pro-Pharmaceuticals
Progen
ProMetic Life Sciences
ProStrakan
Protein Sciences
Protox Therapeutics
PTC Therapeutics
QLT
R&R
Radient Pharmaceuticals
Raptor Pharmaceutical
Reata Pharmaceuticals
Receptor BioLogix
Regeneron
Regulon
Repros Therapeutics
RESprotect
Rexahn
Rigel
Rosetta Genomics
Samyang
Sanofi
Sanofi-Aventis
Santaris Pharma
Sareum
Savient Pharmaceuticals
SBI Biotech
Scancell
Schering-Plough
SciClone Pharmaceuticals
Seattle Genetics
Selvita
Semafore Pharmaceuticals
Senesco Technologies
Sigma-Tau
Simcere Pharmaceuticals
Spear Therapeutics
SRI International
SuperGen
Supratek Pharma
Switch Pharma
SymBio Pharmaceuticals
Symbiotec
SynDevRx
Taiho
Takeda
Targa Therapeutics
Tau Therapeutics
Taxolog
Telik
TetraLogic Pharmaceuticals
Teva
Thallion Pharmaceuticals
Therion Biologics
ThromboGenics
Tigris Pharmaceuticals
to-BBB
ToolGen
TopoTarget
Tracon Pharmaceuticals
Tragara Pharmaceuticals
Transgene
Trion Pharma
UCB
UMN Pharma
Vaccinex
ValiRx
VBL Therapeutics
Velacor Therapeutics
Vernalis
Vertex Pharmaceuticals
Vical
Wilex
Vion Pharmaceuticals
VioQuest
Viragen
Viralytics
ViroMed
ViroTarg
VM Discovery
Wyeth
Xerion
Xoma
Yakult Honsha
YM BioSciences
Zensun
Zhejiang Beta Pharma
Zydus Cadila
131I-tositumomab
AEG-35156
aflibercept
alvocidib
AME-133
anastrozole
apatinib
APG-101
ARQ-197
AS-101
AS-1411
axitinib
bardoxolone methyl
belinostat
bevacizumab
BIBF-1120
bortezomib
bosutinib
brivanib alaninate
BSI-201
BZL-101
canfosfamide hydrochloride
capecitabine
catumaxomab
cediranib
cenersen
cilengitide
cintredekin besudotox
conatumumab
crolibulin
denosumab
dinaciclib
docetaxel
doxifluridine
doxorubicin
dulanermin
endostatin
enzastaurin hydrochloride
epirubicin
everolimus
exemestane
fadrozole
formestane
fosbretabulin tromethamine
fulvestrant
gataparsen
goserelin
GT-111
HBP-347
HE-3235
ibritumomab tiuxetan
idronoxil
imatinib mesilate
imetelstat
INGN-241
interferon
irinotecan hydrochloride
kahalalide F
lapatinib ditosylate
lasofoxifene
lestaurtinib
letrozole
leuprorelin
linifanib
litronesib
lonaprisan
lumiliximab
mapatumumab
midostaurin
mitoxantrone
MKC-1
mocetinostat
motesanib diphosphate
motexafin gadolinium
navitoclax
neratinib
noscapine
Nudoxa
obinutuzumab
oblimersen sodium
ON-01910
Oncohist
OTS-102
paclitaxel
panobinostat
PAT-SC1
patupilone
pazopanib hydrochloride
PBI-1402
PCI-24781
pertuzumab
pirarubicin
plitidepsin
PX-12
quarfloxacin
quinacrine
R-(-)-gossypol
RAF-265
raloxifene hydrochloride
ramucirumab
retaspimycin
ridaforolimus
sagopilone
seliciclib
sorafenib tosylate
SPC-2996
ß-lapachone
Stimuvax
SU-6668
sunitinib malate
talactoferrin alfa
tamoxifen
tegafur + uracil
terameprocol
thymalfasin
tigapotide triflutate
tigatuzumab
tipifarnib
TL-32711
toremifene citrate
trastuzumab
triciribine phosphate
trilostane
triptorelin pamoate
TRU-016
TS-1
vandetanib
volasertib
vosaroxin
XL-147
XL-184
XL-647
Other selected research from the 'Triple Analysis' category:
Competitive Outlook on Non-Antibody Based Cancer Vaccines
Triple Analysis: Leukemia, Melanoma and Peptides
Other selected research from the 'Oncology' category:
Triple Analysis: Lung Cancer, Cancer Vaccines and Peptides
Triple Analysis: Lung Cancer, Lymphoma and Peptides
