This triple analysis focuses on cancer drug development strategies in both Breast Cancer and Colorectal Cancer and by the compound strategy of Antibodies. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.
Below is a short synopsis of each part included in this report:
Part I: Breast Cancer
The breast cancer report part comprises defined and up to date development strategies for 405 breast cancer drugs within the portfolio of 220 investigators, from Ceased to Marketed. This report part extensively analyses 207 identified targets of breast cancer drugs, organized into 193 drug target strategies, and assesses them in breast cancer.
This part is based on the following publication:
Portfolio Analytics and Planning in the Breast Cancer Pipeline - Change is Around the Corner in a Highly Competitive Market Place
Part II: Colorectal Cancer
The colorectal cancer report part comprises defined and up to date development strategies for 347 colorectal cancer drugs within the portfolio of 182 investigators, from Ceased to Marketed. This part extensively analyses their 210 identified drug targets, organized into 205 drug target strategies, and assesses them in eight different compound strategies in colorectal cancer.
This part is based on the following publication:
A Decision Support Tool for Optimizing The Colorectal Cancer Pipeline: From Research and Development to Market
Part III: Antibodies
The cancer antibody drug report part comprises defined and up to date development strategies for 531 antibody drugs in oncology within the portfolio of 196 companies world-wide, from Ceased to Marketed. The report extensively analyses their 255 identified drug targets, organized into 266 drug target strategies, and assesses them in 75 cancer indications.
This part is based on the following publication:
The Global Competitive Landscape of Antibody Drug Development in Cancer: The Faster Route to Consider Your Options and Position of Others
The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:
* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives
* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties
* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities
* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities
* Supporting development of integrative molecule, pathway and disease area strategies
* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment
This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.
Key Topics Covered:
Part I: Breast Cancer
5.1 The Scope of this Report 29
6 Consider the Therapeutic Breast Cancer Target for the Highest Therapeutic Outcome and Return on Investment (207 Drug Targets) 33-376
7 The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Strategies Identified in the Breast Cancer Therapeutic Pipeline? (193 Drug Target Strategies and 405 Drugs) 377-441
8 Compound Strategies at Work: Competitive Benchmarking of Breast Cancer Drugs by Compound Strategy (8 Different Compound Strategies) 442-488
9 Pipeline and Portfolio Planning: Competitive Benchmarking of Breast Cancer Therapeutic Pipeline by Investigator (220 Investigators) 489-891
11 Drug Index 893
12 Company Index 905
Figures: Includes 7 Figures
Tables: Includes 274 Tables
Total Number of Pages: 913
Part II: Colorectal Cancer
5.1 The Scope of this Report 28
6 Consider the Therapeutic Target Among Colorectal Cancer Drugs for the Highest Therapeutic Outcome and Return on Investment (210 Drug Targets) 32-451
7 Emerging New Products to Established Ones: Drug Target Strategies of Colorectal Cancer Drugs by their Highest Stage of Development (205 Drug Target Strategies and 347 Colorectal Cancer Drugs) 452-699
8 Compound Strategies at Work: Competitive Benchmarking of Colorectal Cancer Drugs by Compound Strategy (8 Compound Strategies) 700-745
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Colorectal Cancer Drug Pipeline by Investigator (182 Companies) 746-1,039
10 Disclaimer 1040
11 Drug Index 1041
12 Company Index 1050
Figures: Includes 6 Figures
Tables: Includes 242 Tables
Total Number of Pages: 1,056
Part III: Antibodies
5.1 The Scope of this Report 35
6 Consider the Therapeutic Target Among Antibody Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (255 Drug Targets) 39-430
7 Emerging New Products to Established Ones: Drug Target Strategies of Antibody Drugs in Oncology by their Highest Stage of Development (266 Drug Targets Strategies and 531 Antibody Drugs) 431-768
8 Selecting Cancer Indication for Antibody Drugs (75 Cancer Indications) 769-893
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Antibody Drug Pipeline in Oncology by Investigator (196 Investigators and 531 Antibody Drugs) 894-1,916
10 Disclaimer 1917
11 Drug Index 1918
12 Company Index 1934
Figures: Includes 5 Figures
Tables: Includes 347 Tables
Total Number of Pages: 1,944
A&G Pharmaceutical
Abbott
Abiogen
Ablynx
Abraxis BioScience
AC Immune
Acceleron Pharma
Access
Actinium Pharmaceuticals
Active Biotech
Adherex
Advaxis
AEgera
AEterna Zentaris
Affibody
Affimed Therapeutics
Affitech
AGY Therapeutics
Aida Pharmaceuticals
Alchemia
Alder Biopharmaceuticals
Alethia Biotherapeutics
Alexion
Alfacell
Algeta
Allos Therapeutics
Alnis Biosciences
Alnylam
AlphaVax
Alseres Pharmaceuticals
ALSP
Altor BioScience
Amgen
Amorfix Life Sciences
Anavex Life Sciences
AngioChem
Antisense Pharma
Antisoma
Aphios
Apotex
Apricus Biosciences
Apthera
Arana Therapeutics
Arca biopharma
Archer Biosciences
arGEN-X
Ariad
ArQule
Array BioPharma
Ascend Therapeutics
Astellas
AstraZeneca
Attenuon
Avaxia
AVEO
AVI BioPharma
Bavarian Nordic
Bayer
Berkeley Lab
Betagenon
Betapharma
BioAlliance Pharma
Biocompatibles
Biocon
Biogen Idec
BioInvent
Biolex
BioLineRx
Bionovo
BioNumerik
Biosceptre
Biotecnol
Biotest
BioVex
Boehringer Ingelheim
Bristol-Myers Squibb
BTG
Callisto Pharmaceuticals
Can-Fite BioPharma
Cancer Advances
Cancer Innovations
Cancer Research Technology
Cel-Sci
Celator Pharmaceuticals
Celera
Celgene
Cell Genesys
Cell Therapeutics
Celldex Therapeutics
Cellmid
Celltrion
Celsion
Celtic Pharma
Center of Molecular Immunology
Cephalon
CG Therapeutics
ChemGenex Pharmaceuticals
Chemokine Therapeutics
Chiesi
Choongwae
Circadian Technologies
Clavis Pharma
CompleGen
Cosmo Pharmaceuticals
CSL
CuraGen
CureTech
Curis
Cyclacel
Cylene Pharmaceuticals
Cynvec
CytImmune Sciences
Cytokinetics
CytRx
Daiichi Sankyo
Dainippon Sumitomo Pharma
Debiopharm
Deciphera Pharmaceuticals
Dendreon
DiaMedica
Dompe
Dong-A
Dongkook Pharm
Douglas
Dr Reddy’s
Dyax
Dynavax Technologies
ECI
EGEN Inc
Eisai
Elan
Elara Pharmaceuticals
Eli Lilly
Emergent BioSolutions
Endoceutics
Enkam Pharmaceuticals
EntreMed
Enzon
Epeius Biotechnologies
EpiCept
Epitomics
Etubics
Eucodis
EUSA Pharma
Exelixis
Faron Pharmaceuticals
FasTrack Pharmaceuticals
Favrille
Femta Pharmaceuticals
FibroGen
Five Prime Therapeutics
Fresenius
Fusion Antibodies
Galaxy Biotech
GammaCan
Ganymed Pharmaceuticals
Gene Techno Science
Genencor
Genentech
Generex
Genmab
Genomic Systems
GenPat77
Genta
GenVec
Genzyme
Geron
Gilead Sciences
GlaxoSmithKline
Gliknik
Gloucester Pharmaceuticals
GlycoGenesys
Glycotope
GlyTag
Got-a-Gene
Gradalis
Green Cross
Hawthorn Pharmaceuticals
Heidelberg Pharma
Hoffmann-La Roche
Hospira
Human Genome Sciences
Idera Pharmaceuticals
IDM Pharma
IkerChem
ImClone Systems
IMED
Immune Pharmaceuticals
ImmunoCellular Therapeutics
Immunocore
ImmunoGen
Immunomedics
Immunotope
Immutep
Incyte Corporation
Inex
Infinity Pharmaceuticals
Innate Pharma
InNexus Biotechnology
Inovio
Insmed
Insys Therapeutics
Intarcia Therapeutics
Intezyne Technologies
Intracel
Intradigm
Introgen Therapeutics
Ipsen
ISA Pharmaceuticals
Isis Pharmaceuticals
ISU ABXIS
Ivy Medical Chemicals
Jennerex Biotherapeutics
Johnson & Johnson
Kaketsuken
KaloBios
Kiadis
Kirin Pharma
Kissei
Kyowa Hakko Kirin
Kyto Biopharma
Labopharm
LEAD Therapeutics
Leo
LFB Biotechnologies
LG Life Sciences
Ligand
Lorus Therapeutics
MacroGenics
Marillion Pharmaceuticals
MAT Biopharma
MDRNA
Meda
Medarex
MediGene
MedImmune
Mediolanum
Meiji
Menarini
Merck & Co
Merck KGaA
Merrimack
Mersana Therapeutics
MethylGene
Micromet
Mitsubishi Tanabe Pharma
MolMed
Mologen
Mycenax
NanoMed Pharmaceuticals
Nektar Therapeutics
Nemod Biotherapeutics
NeoPharm
Neovacs
Nerviano Medical Sciences
Neuren
NexGenix Pharmaceuticals
NicOx
Nidus Laboratories
NIH
Nippon Kayaku
NKT Therapeutics
Non-industrial source
Northwest Biotherapeutics
Novartis
Novogen
Nycomed Pharma
OncoGenex Pharmaceuticals
OncoMed
OncoMune
Onconova
Oncothyreon
Oncozyme Pharma
Onyvax
Orca Therapeutics
Orchestra Therapeutics
Orion Pharma
OSI Pharmaceuticals
Oxford BioMedica
OXiGENE
Paladin Labs
Panacea
PanaGin
PanGenetics
Pantarhei Bioscience
Patrys
Pepscan Therapeutics
PepTcell
Peregrine Pharmaceuticals
Perseus Proteomics
Pfizer
Pharmaclon
Pharmacyclics
PharmaGap
PharmaMar
Pharmexa
PheneX
Philogen
Pierre Fabre
Plexxikon
POZEN
Prima Biomed
Pro-Pharmaceuticals
ProCell Therapeutics
Prochon Biotech
Progenics Pharmaceuticals
ProStrakan
Protherics
Protox Therapeutics
PTC Therapeutics
R&R
Radient Pharmaceuticals
Ramot
Raptor Pharmaceutical
Recepta biopharma
Receptor BioLogix
Regeneron
Regulon
Repros Therapeutics
RESprotect
Rigel
Samyang
Sanofi-Aventis
Santaris Pharma
Sareum
Savient Pharmaceuticals
SBI Biotech
Scancell
Schering-Plough
Seattle Genetics
Selvita
Semafore Pharmaceuticals
Shenogen
Shire
Sigma-Tau
Simcere Pharmaceuticals
Spirogen
SRI International
Stainwei Biotech
Sunol Molecular
SuperGen
SuppreMol
Supratek Pharma
Switch Pharma
Symphogen
Synageva BioPharma
SynDevRx
SynerGene Therapeutics
Synta Pharmaceuticals
Taiho
Takeda
Talon Therapeutics
Targa Therapeutics
Targepeutics
Tau Therapeutics
Taxolog
TeGenero
Telik
Teva
Thallion Pharmaceuticals
The Genetics Company
Therapure Biopharma
Therion Biologics
ThromboGenics
Titan Pharmaceuticals
to-BBB
Tolerx
TopoTarget
Tracon Pharmaceuticals
Tragara Pharmaceuticals
Transgene
Trillium Therapeutics
Trion Pharma
UCB
United Therapeutics
Vaccinex
Wakunaga
VasGene Therapeutics
Vernalis
Vertex Pharmaceuticals
Vical
Wilex
Vion Pharmaceuticals
VioQuest
VioQuest Pharmaceuticals
Viragen
Viralytics
ViroMed
ViroTarg
Viventia Biotech
Wyeth
XBiotech
Xencor
Xerion
Xoma
Y’s Therapeutics
Yakult Honsha
YM BioSciences
Zenotech
Zensun
Zhejiang Beta Pharma
Zydus Cadila
131I-tositumomab
abagovomab
aflibercept
alemtuzumab
AMG-386
anastrozole
Angiozyme
bevacizumab
brentuximab vedotin
brivanib alaninate
BSI-201
capecitabine
catumaxomab
cediranib
cetuximab
denosumab
docetaxel
doxifluridine
doxorubicin
epirubicin
everolimus
exemestane
fadrozole
farletuzumab
formestane
fulvestrant
galiximab
gemtuzumab ozogamicin
girentuximab
goserelin
ibritumomab tiuxetan
inotuzumab ozogamicin
interferon
interferon gamma
ipilimumab
irinotecan bead
irinotecan hydrochloride
lapatinib ditosylate
lasofoxifene
letrozole
leuprorelin
lumiliximab
MGN-1703
mitoxantrone
naptumomab estafenatox
necitumumab
neratinib
nimotuzumab
Nudoxa
obinutuzumab
ofatumumab
oregovomab
paclitaxel
panitumumab
pazopanib hydrochloride
perifosine
pertuzumab
pirarubicin
raloxifene hydrochloride
raltitrexed
ramucirumab
Reditux
regorafenib
rituximab
Stimuvax
sunitinib malate
tamoxifen
tegafur + uracil
tegafur + uracil + leucovorin
toremifene citrate
trastuzumab
trilostane
triptorelin pamoate
TS-1
zalutumumab
zanolimumab
Other selected research from the 'Triple Analysis' category:
Triple Analysis: Breast Cancer, Lymphoma and Protein Kinase Inhibitors
Triple Analysis: Breast Cancer, Colorectal Cancer and Antibodies
Other selected research from the 'Oncology' category:
Triple Analysis: Breast Cancer, Colorectal Cancer and Melanoma
Financial Markets Research: ASCO Review Part II - A summary of highlights presented at the ASCO 2006 Annual Meeting
