This triple analysis focuses on cancer drug development strategies in both Breast Cancer and Melanoma and by the mechanism/target/effect of Apoptosis. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.
Below is a short synopsis of each part included in this report:
Part I: Breast Cancer
The breast cancer report part comprises defined and up to date development strategies for 405 breast cancer drugs within the portfolio of 220 investigators, from Ceased to Marketed. This report part extensively analyses 207 identified targets of breast cancer drugs, organized into 193 drug target strategies, and assesses them in breast cancer.
This part is based on the following publication:
Portfolio Analytics and Planning in the Breast Cancer Pipeline - Change is Around the Corner in a Highly Competitive Market Place
Part II: Melanoma
The melanoma report part comprises defined and up to date development strategies for 218 melanoma drugs within the portfolio of 138 investigators, from Ceased to Marketed. This part extensively analyses their 170 identified drug targets, organized into 151 drug target strategies, and assesses them in eight different compound strategies in melanoma.
This part is based on the following publication:
A Decision Support Tool for Optimizing the Melanoma Pipeline: From Research and Development to Market
Part III: Apoptosis
The apoptotic cancer drug report part comprises defined and up to date development strategies for 234 drugs in oncology within the portfolio of 158 companies world-wide, from Ceased to Marketed. The report extensively analyses their 181 identified drug targets, organized into 157 drug target strategies, and assesses them in 69 cancer indications.
This part is based on the following publication:
Commercializing Apoptotic Drugs in Cancer: The Faster Route to Consider Your Options and Position of Others
The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:
* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives
* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties
* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities
* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities
* Supporting development of integrative molecule, pathway and disease area strategies
* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment
This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.
Key Topics Covered:
Part I: Breast Cancer
5.1 The Scope of this Report 29
6 Consider the Therapeutic Breast Cancer Target for the Highest Therapeutic Outcome and Return on Investment (207 Drug Targets) 33-376
7 The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Strategies Identified in the Breast Cancer Therapeutic Pipeline? (193 Drug Target Strategies and 405 Drugs) 377-441
8 Compound Strategies at Work: Competitive Benchmarking of Breast Cancer Drugs by Compound Strategy (8 Different Compound Strategies) 442-488
9 Pipeline and Portfolio Planning: Competitive Benchmarking of Breast Cancer Therapeutic Pipeline by Investigator (220 Investigators) 489-891
11 Drug Index 893
12 Company Index 905
Figures: Includes 7 Figures
Tables: Includes 274 Tables
Total Number of Pages: 913
Part II: Melanoma
5.1 The Scope of this Report 25
6 Consider the Therapeutic Target Among Melanoma Drugs for the Highest Therapeutic Outcome and Return on Investment (170 Drug Targets) 29-363
7 Emerging New Products to Established Ones: Drug Target Strategies of Melanoma Drugs by their Highest Stage of Development (151 Drug Target Strategies and 218 Melanoma Drugs) 364-538
8 Compound Strategies at Work: Competitive Benchmarking of Melanoma Drugs by Compound Strategy (8 Compound Strategies) 539-574
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Melanoma Drug Pipeline by Investigator (138 Companies) 575-766
10 Disclaimer 767
11 Drug Index 768
12 Company Index 773
Figures: Includes 6 Figures
Tables: Includes 196 Tables
Total Number of Pages: 777
Part III: Apoptosis
5.1 The Scope of this Report 33
6 Consider the Therapeutic Target Among Apoptotic Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (181 Drug Targets) 37-416
7 Emerging New Products to Established Ones: Drug Target Strategies of Apoptotic Drugs in Oncology by their Highest Stage of Development (157 Drug Target Strategies and 234 Drugs) 417-622
8 Compound Strategies at Work: Competitive Benchmarking of Apoptotic Cancer Drugs by Compound Strategy(7 Compound Strategies) 623-660
9 Selecting Indication for Apoptotic Drugs in Oncology (69 Cancer Indications) 661-776
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Apoptotic Drug Pipeline in Oncology by Investigator (158 Investigators and 234 Drugs) 777-1601
Disclaimer 1602
11 Drug Index 1603
12 Company Index 1611
Figures: Includes 7 Figures
Tables: Includes 315 Tables
Total Number of Pages: 1,617
3SBio
A&G Pharmaceutical
Abbott
Abiogen
Abraxis BioScience
Access
Actelion
Adherex
Advanced Life Sciences
Advaxis
AEgera
AEterna Zentaris
Affibody
Aida Pharmaceuticals
Aileron Therapeutics
Alchemia
Alethia Biotherapeutics
Alnis Biosciences
Alnylam
AlphaVax
Alseres Pharmaceuticals
Altor BioScience
Ambit Biosciences
Ambrilia Biopharma
Amgen
Anadys Pharmaceuticals
Anaphore
Anavex Life Sciences
AngioChem
Antisense Pharma
Antisoma
Aphios
Apogenix
ApopLogic Pharmaceuticals
Apotex
Apthera
Archer Biosciences
Ariad
Arno Therapeutics
ArQule
Array BioPharma
Ascend Therapeutics
Ascenta Therapeutics
Astellas
Astex Therapeutics
AstraZeneca
Attenuon
AVI BioPharma
Avila Therapeutics
Basilea Pharmaceutica
Bavarian Nordic
Bayer
Betagenon
Bio-Medisinsk Innovasjon
BioAlliance Pharma
BioAxone
Biocad
Biogen Idec
BioInvent
Biokine Therapeutics
BioLineRx
Biomas
Bionovo
BioNumerik
Biosceptre
Biotecnol
BioVex
Boehringer Ingelheim
Bristol-Myers Squibb
BTG
Callisto Pharmaceuticals
Cancer Research Technology
CDG Therapeutics
Cel-Sci
Celera
Cell Genesys
Cell Therapeutics
Celldex Therapeutics
Celsion
Celtic Pharma
Center of Molecular Immunology
Cephalon
ChemGenex Pharmaceuticals
ChemoCentryx
Chemokine Therapeutics
Chiesi
Chlorogen
Chroma Therapeutics
CJ Corp
Clavis Pharma
Cleveland BioLabs
CombinatoRx
CompleGen
Coronado Biosciences
Cosmo Pharmaceuticals
Critical Outcome Technologies
CSL
Curis
Cyclacel
Cylene Pharmaceuticals
Cynvec
CytImmune Sciences
Cytochroma
Cytokinetics
CytRx
Daewoong
Daiichi Sankyo
Dainippon Sumitomo Pharma
Dara Biosciences
Debiopharm
Deciphera Pharmaceuticals
Dendreon
DeveloGen
DNAVEC
Dong-A
Dongkook Pharm
Douglas
ECI
Eisai
Elan
Elara Pharmaceuticals
Eleos
Eli Lilly
Emergent BioSolutions
Endoceutics
Enkam Pharmaceuticals
EntreMed
Enzon
Epeius Biotechnologies
EpiCept
Erimos
Eucodis
Exelixis
Facet Biotech
Flamel Technologies
Fresenius
Genentech
Generex
Genmab
Genta
GenVec
Genzyme
Gerolymatos
Geron
GlaxoSmithKline
Gloucester Pharmaceuticals
GlycoGenesys
Glycotope
GlyTag
Got-a-Gene
GPC Biotech
Green Cross
Harbor BioSciences
Heidelberg Pharma
Hemispherx Biopharma
Hoffmann-La Roche
Hospira
Human Genome Sciences
Ichor Medical Systems
Idera Pharmaceuticals
Immunocore
ImmunoGen
Immunomedics
Immunotope
Immutep
Incyte Corporation
Inex
Infinity Pharmaceuticals
Innate Pharma
InNexus Biotechnology
Inotek
Inovio
Insmed
Insys Therapeutics
Intarcia Therapeutics
Intezyne Technologies
Intradigm
Intrexon
Introgen Therapeutics
Ipsen
Isis Pharmaceuticals
ISU ABXIS
Jennerex Biotherapeutics
Johnson & Johnson
Kalypsys
Karyon-CTT
Keryx Biopharmaceuticals
Kiadis
Kyowa Hakko Kirin
LEAD Therapeutics
Leo
LG Life Sciences
Ligand
Lorus Therapeutics
Mannkind
Marillion Pharmaceuticals
MDRNA
Meda
Medarex
MediGene
MedImmune
Mediolanum
Medisyn Technologies
Meiji
Menarini
Merck & Co
Merck KGaA
MethylGene
Micromet
Mitsubishi Tanabe Pharma
Mochida
Mojave Therapeutics
MolMed
Mologen
NanoMed Pharmaceuticals
Nektar Therapeutics
Nemod Biotherapeutics
NeoPharm
Nereus Pharmaceuticals
Nerviano Medical Sciences
NexGenix Pharmaceuticals
Nidus Laboratories
NIH
Nippon Kayaku
Nippon Shinyaku
Non-industrial source
Novacea
NovaLead
Novartis
Novelix
Novogen
Oncalis
OncoGenex Pharmaceuticals
OncoMune
Onconova
Oncothyreon
Orion Pharma
OSI Pharmaceuticals
Oxford BioMedica
OXiGENE
Paladin Labs
PanaGin
Pantarhei Bioscience
Patrys
PBL Therapeutics
PepTcell
Peregrine Pharmaceuticals
Pfizer
Pharmacyclics
PharmaGap
PharmaMar
Pharmexa
Pharminox
PheneX
Philogen
PhiloGene
Pierre Fabre
Piramal
Plexxikon
Pro-Pharmaceuticals
Progen
ProMetic Life Sciences
ProStrakan
Protox Therapeutics
PTC Therapeutics
QLT
R&R
Radient Pharmaceuticals
Raptor Pharmaceutical
Reata Pharmaceuticals
Receptor BioLogix
Regeneron
Regulon
Repros Therapeutics
RESprotect
Rigel
Rosetta Genomics
Samyang
Sanofi
Sanofi-Aventis
Santaris Pharma
Sareum
Savient Pharmaceuticals
SBI Biotech
Scancell
Schering-Plough
SciClone Pharmaceuticals
Seattle Genetics
Selvita
Semafore Pharmaceuticals
Senesco Technologies
Shire
Sigma-Tau
Simcere Pharmaceuticals
Solbec Pharmaceuticals
Spirogen
SRI International
SuperGen
Supratek Pharma
Swedish Orphan Biovitrum
Switch Pharma
SymBio Pharmaceuticals
Symbiotec
Taiho
Takeda
Targa Therapeutics
Targepeutics
Tau Therapeutics
Taxolog
Telik
TetraLogic Pharmaceuticals
Teva
Thallion Pharmaceuticals
Therion Biologics
Tigris Pharmaceuticals
to-BBB
TopoTarget
Tracon Pharmaceuticals
Tragara Pharmaceuticals
Transgene
Trion Pharma
UMN Pharma
Vaccinex
ValiRx
VaxOnco
VBL Therapeutics
Vectura
Velacor Therapeutics
Vernalis
Vertex Pharmaceuticals
Vical
Wilex
Vion Pharmaceuticals
VioQuest
Viragen
Viralytics
ViroMed
ViroTarg
VM Discovery
Wyeth
Xerion
Xoma
Yakult Honsha
YM BioSciences
York Pharma
Zensun
Zhejiang Beta Pharma
Zydus Cadila
ZymoGenetics
131I-tositumomab
AEG-35156
AG-14699
agatolimod
aldesleukin
ALT-801
alvocidib
AME-133
anastrozole
APG-101
APO-866
ARQ-197
AS-101
AS-1411
astuprotimut-r
axitinib
bardoxolone methyl
belinostat
bevacizumab
BMS-663513
bortezomib
bosentan
bosutinib
BSI-201
BZL-101
canfosfamide hydrochloride
capecitabine
catumaxomab
cenersen
cintredekin besudotox
conatumumab
cositecan
crolibulin
dasatinib
decitabine
denenicokin
denosumab
dinaciclib
docetaxel
dovitinib lactate
doxifluridine
doxorubicin
dulanermin
EMD-273063
endostatin
entinostat
enzastaurin hydrochloride
epirubicin
everolimus
exemestane
Exherin
fadrozole
formestane
fosbretabulin tromethamine
fresolimumab
fulvestrant
gataparsen
gefitinib
glembatumumab
golnerminogene pradenovec
goserelin
GT-111
GV-1001
HE-3235
histamine dihydrochloride
ibritumomab tiuxetan
idronoxil
imatinib mesilate
imetelstat
IMP-321
INGN-241
interferon
interferon-alpha
interferon-alpha2
interferon-alpha2a
interferon-alpha2b
interferon-beta
interleukin-2, 2nd-generation
intetumumab
IPH-1101
ipilimumab
irinotecan hydrochloride
ispinesib mesylate
JX-594
kahalalide F
L19-IL2
lapatinib ditosylate
lasofoxifene
lestaurtinib
letrozole
leuprorelin
LipoVIL12
litronesib
lonaprisan
lumiliximab
mapatumumab
MDX-1106
MetXia
MGN-1601
mitoxantrone
MKC-1
MKC-1106-MT
mocetinostat
motexafin gadolinium
navitoclax
neratinib
noscapine
Nudoxa
obinutuzumab
oblimersen sodium
ON-01910
Oncohist
OncoVEX GM-CSF
P-276-00
paclitaxel
panobinostat
PAT-SC1
pazopanib hydrochloride
PBI-1402
PCI-24781
peginterferon alfa-2b
perifosine
pertuzumab
pirarubicin
plitidepsin
PLX-4032
PX-12
quarfloxacin
quinacrine
R-(-)-gossypol
RAF-265
raloxifene hydrochloride
ramucirumab
retaspimycin
sagopilone
sargramostim
seliciclib
selumetinib
sodium stibogluconate
SPC-2996
ß-lapachone
Stimuvax
SU-6668
sunitinib malate
tamoxifen
tegafur + uracil
terameprocol
thymalfasin
tigapotide triflutate
tigatuzumab
tipifarnib
TL-32711
topotecan
toremifene citrate
trabedersen
trastuzumab
tremelimumab
triciribine phosphate
trilostane
triptorelin pamoate
TRU-016
TS-1
velimogene aliplasmid
veliparib
volasertib
volociximab
vosaroxin
XL-147
XL-647
YM-155
Other selected research from the 'Triple Analysis' category:
Triple Analysis: Colorectal Cancer, Lung Cancer and Melanoma
Triple Analysis: Lung Cancer, Apoptosis and Protein Kinase Inhibitors
Other selected research from the 'Oncology' category:
Triple Analysis: Lymphoma, Apoptosis and Antibodies
The Commercial Success of Cancer Therapeutic Antibodies - The Formation of a Second Wave
