This triple analysis focuses on cancer drug development strategies in Colorectal Cancer, Melanoma and Prostate Cancer. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.
Below is a short synopsis of each part included in this report:
Part I: Colorectal Cancer
The colorectal cancer report part comprises defined and up to date development strategies for 347 colorectal cancer drugs within the portfolio of 182 investigators, from Ceased to Marketed. This part extensively analyses their 210 identified drug targets, organized into 205 drug target strategies, and assesses them in eight different compound strategies in colorectal cancer.
This part is based on the following publication:
A Decision Support Tool for Optimizing The Colorectal Cancer Pipeline: From Research and Development to Market
Part II: Melanoma
The melanoma report part comprises defined and up to date development strategies for 218 melanoma drugs within the portfolio of 138 investigators, from Ceased to Marketed. This part extensively analyses their 170 identified drug targets, organized into 151 drug target strategies, and assesses them in eight different compound strategies in melanoma.
This part is based on the following publication:
A Decision Support Tool for Optimizing the Melanoma Pipeline: From Research and Development to Market
Part III: Prostate Cancer
The prostate cancer report part comprises defined and up to date development strategies for 346 prostate cancer drugs within the portfolio of 198 investigators, from Ceased to Marketed. This report part extensively analyses 202 identified targets of prostate cancer drugs, organized into 187 drug target strategies, and assesses them in prostate cancer.
This part is based on the following publication:
A Decision Support Tool for Optimizing the Prostate Cancer Pipeline: From Research and Development to Market
The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:
* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives
* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties
* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities
* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities
* Supporting development of integrative molecule, pathway and disease area strategies
* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment
This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.
Key Topics Covered:
Part I: Colorectal Cancer
5.1 The Scope of this Report 28
6 Consider the Therapeutic Target Among Colorectal Cancer Drugs for the Highest Therapeutic Outcome and Return on Investment (210 Drug Targets) 32-451
7 Emerging New Products to Established Ones: Drug Target Strategies of Colorectal Cancer Drugs by their Highest Stage of Development (205 Drug Target Strategies and 347 Colorectal Cancer Drugs) 452-699
8 Compound Strategies at Work: Competitive Benchmarking of Colorectal Cancer Drugs by Compound Strategy (8 Compound Strategies) 700-745
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Colorectal Cancer Drug Pipeline by Investigator (182 Companies) 746-1,039
10 Disclaimer 1040
11 Drug Index 1041
12 Company Index 1050
Figures: Includes 6 Figures
Tables: Includes 242 Tables
Total Number of Pages: 1,056
Part II: Melanoma
5.1 The Scope of this Report 25
6 Consider the Therapeutic Target Among Melanoma Drugs for the Highest Therapeutic Outcome and Return on Investment (170 Drug Targets) 29-363
7 Emerging New Products to Established Ones: Drug Target Strategies of Melanoma Drugs by their Highest Stage of Development (151 Drug Target Strategies and 218 Melanoma Drugs) 364-538
8 Compound Strategies at Work: Competitive Benchmarking of Melanoma Drugs by Compound Strategy (8 Compound Strategies) 539-574
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Melanoma Drug Pipeline by Investigator (138 Companies) 575-766
10 Disclaimer 767
11 Drug Index 768
12 Company Index 773
Figures: Includes 6 Figures
Tables: Includes 196 Tables
Total Number of Pages: 777
Part III: Prostate Cancer
5.1 The Scope of this Report 28
6 Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (202 Drug Targets) 32-383
7 Emerging New Products to Established Ones: Drug Target Strategies by their Highest Stage of Development in the Prostate Cancer Pipeline (187 Drug Target Strategies and 346 Drugs) 384-438
8 Compound Strategies at Work: Competitive Benchmarking of Prostate Cancer Drugs by Compound Strategy (8 Different Compound Strategies) 439-485
9 Pipeline and Portfolio Planning: Competitive Benchmarking of Prostate Cancer Therapeutic Pipeline by Investigator (198 Investigators) 486-820
11 Drug Index 822
12 Company Index 831
Figures: Includes 6 Figures
Tables: Includes 257 Tables
Total Number of Pages: 838
3SBio
Abbott
Abiogen
Abraxis BioScience
Actelion
Active Biotech
Adherex
Advanced Life Sciences
Advantagene
Advaxis
AEgera
Aeterna Zentaris
Affimed Therapeutics
Alchemia
Alethia Biotherapeutics
Allos Therapeutics
Alnylam
AlphaVax
Alseres Pharmaceuticals
Altor BioScience
Ambit Biosciences
Ambrilia Biopharma
Amgen
Anavex Life Sciences
AngioChem
Antisense Pharma
Antisoma
Aphios
ApopLogic Pharmaceuticals
Apotex
Apthera
Archer Biosciences
Ariad
ArQule
Array BioPharma
Astellas
Astex Therapeutics
AstraZeneca
Attenuon
AVEO
AVI BioPharma
Bavarian Nordic
Bayer
Bellicum Pharmaceuticals
Betapharma
Bio-Medisinsk Innovasjon
BioAlliance Pharma
Biocompatibles
Biogen Idec
Biokine Therapeutics
BioNumerik
Biosceptre
Biostar
Biotecnol
BioVex
Boehringer Ingelheim
Bristol-Myers Squibb
BTG
Cadila
Can-Fite BioPharma
Cancer Advances
Cancer Research Technology
CDG Therapeutics
Cel-Sci
Celator Pharmaceuticals
Celera
Celgene
Cell Genesys
Cell Therapeutics
Celldex Therapeutics
Cellmid
Celsion
Celtic Pharma
Center of Molecular Immunology
Cephalon
CG Therapeutics
ChemGenex Pharmaceuticals
Chemokine Therapeutics
Choongwae
Circadian Technologies
CJ Corp
Clavis Pharma
Cosmo Pharmaceuticals
CSL
CuraGen
CureTech
Curis
Cyclacel
Cylene Pharmaceuticals
Cynvec
CytImmune Sciences
Cytokinetics
Daewoong
Daiichi Sankyo
Dainippon Sumitomo Pharma
Dara Biosciences
Debiopharm
Deciphera Pharmaceuticals
Dendreon
DNAVEC
Dong-A
Dongkook Pharm
Dynavax Technologies
ECI
EGEN Inc
Eisai
Elan
Eli Lilly
Endocyte
Enkam Pharmaceuticals
EntreMed
Enzon
Epeius Biotechnologies
EpiCept
Etubics
Exelixis
Facet Biotech
FasTrack Pharmaceuticals
Flamel Technologies
Generex
Genmab
Genta
GenVec
Genzyme
Geron
Gilead Sciences
GlaxoSmithKline
Gloucester Pharmaceuticals
GlycoGenesys
Got-a-Gene
Gradalis
Green Cross
Heidelberg Pharma
Hemispherx Biopharma
Hoffmann-La Roche
Human Genome Sciences
Ichor Medical Systems
Idera Pharmaceuticals
IkerChem
Immunocore
ImmunoGen
Immunomedics
Immutep
Incyte Corporation
Infinity Pharmaceuticals
Innate Pharma
InNexus Biotechnology
Inotek
Inovio
Insmed
Insys Therapeutics
Intrexon
Introgen Therapeutics
Ipsen
ISA Pharmaceuticals
Isis Pharmaceuticals
Ivy Medical Chemicals
Jennerex Biotherapeutics
Johnson & Johnson
Kalypsys
Karyon-CTT
Kiadis
Kyowa Hakko Kirin
Labopharm
LEAD Therapeutics
Leo
LG Life Sciences
Ligand
Lorus Therapeutics
MacroGenics
Mannkind
Marillion Pharmaceuticals
Meda
Medarex
MediGene
MedImmune
Mediolanum
Medisyn Technologies
Menarini
Merck & Co
Merck KGaA
Merrimack
Mersana Therapeutics
MethylGene
Micromet
Mitsubishi Tanabe Pharma
Mochida
Mojave Therapeutics
MolMed
Mologen
Nektar Therapeutics
NeoPharm
Nerviano Medical Sciences
NicOx
Nippon Kayaku
Non-industrial source
Northwest Biotherapeutics
Novartis
Novogen
Nycomed Pharma
Oncalis
OncoGenex Pharmaceuticals
OncoMed
Onconova
Oncothyreon
Oncovir
Oncozyme Pharma
Onyvax
Orca Therapeutics
Orchestra Therapeutics
Orion Pharma
OSI Pharmaceuticals
Oxford BioMedica
OXiGENE
Paladin Labs
PanaGin
Pantarhei Bioscience
PBL Therapeutics
Pepscan Therapeutics
Pfizer
Pharmaclon
Pharmacyclics
PharmaGap
PharmaMar
Pharmexa
Philogen
PhiloGene
Pierre Fabre
Piramal
Plexxikon
POZEN
Pro-Pharmaceuticals
Progen
Progenics Pharmaceuticals
ProStrakan
Protherics
Protox Therapeutics
Reata Pharmaceuticals
Receptor BioLogix
Regeneron
Regulon
Rexahn
Rigel
Samyang
Sanofi-Aventis
Santaris Pharma
Sareum
Scancell
SciClone Pharmaceuticals
Seattle Genetics
Semafore Pharmaceuticals
Shire
Sigma-Tau
Simcere Pharmaceuticals
Solbec Pharmaceuticals
Spirogen
SRI International
SuperGen
Supratek Pharma
Swedish Orphan Biovitrum
Switch Pharma
SynDevRx
Synta Pharmaceuticals
Taiho
Takeda
Talon Therapeutics
Targa Therapeutics
Targepeutics
Tau Therapeutics
Taxolog
Telik
Thallion Pharmaceuticals
The Genetics Company
Therion Biologics
ThromboGenics
Titan Pharmaceuticals
TopoTarget
Tracon Pharmaceuticals
Transgene
Trion Pharma
United Biomedical
Vaxon Biotech
VaxOnco
VBL Therapeutics
Vectura
Vertex Pharmaceuticals
Vical
Wilex
Vion Pharmaceuticals
VioQuest
VioQuest Pharmaceuticals
Viralytics
ViroTarg
Wyeth
Xerion
Xoma
Yakult Honsha
YM BioSciences
York Pharma
ZymoGenetics
abarelix
abiraterone acetate
aflibercept
AG-14699
agatolimod
aldesleukin
ALT-801
Angiozyme
APO-866
astuprotimut-r
axitinib
bardoxolone methyl
belinostat
bevacizumab
bicalutamide
BMS-663513
bortezomib
bosentan
brivanib alaninate
buserelin
capecitabine
catumaxomab
cediranib
celecoxib
cetuximab
cositecan
dasatinib
DCVax-prostate
decitabine
degarelix
denenicokin
denosumab
deslorelin
docetaxel
dovitinib lactate
doxifluridine
dutasteride
EMD-273063
endostatin
entinostat
epirubicin
estramustine phosphate sodium
ethinyl estradiol sulfonate
everolimus
Exherin
flutamide
fresolimumab
gefitinib
glembatumumab
golnerminogene pradenovec
goserelin
GT-111
GV-1001
histamine dihydrochloride
histrelin
imatinib mesilate
IMP-321
INGN-241
interferon gamma
interferon-alpha
interferon-alpha2
interferon-alpha2a
interferon-alpha2b
interferon-beta
interleukin-2, 2nd-generation
intetumumab
IPH-1101
ipilimumab
irinotecan bead
irinotecan hydrochloride
ispinesib mesylate
JX-594
kahalalide F
L19-IL2
leuprolide
LipoVIL12
MDV-3100
MDX-1106
MetXia
MGN-1601
MGN-1703
MKC-1106-MT
nadroparin
nilutamide
oblimersen sodium
OncoVEX GM-CSF
P-276-00
panitumumab
peginterferon alfa-2b
perifosine
plitidepsin
PLX-4032
raltitrexed
ramucirumab
regorafenib
retaspimycin
sagopilone
sargramostim
selumetinib
sodium stibogluconate
sunitinib malate
tegafur + uracil
tegafur + uracil + leucovorin
thymalfasin
topotecan
toremifene citrate
trabedersen
tremelimumab
triptorelin
triptorelin pamoate
TS-1
velimogene aliplasmid
veliparib
volociximab
YM-155
zibotentan
Other selected research from the 'Triple Analysis' category:
Triple Analysis: Breast Cancer, Colorectal Cancer and Peptides
Triple Analysis: Colorectal Cancer, Pancreatic Cancer and Peptides
Other selected research from the 'Oncology' category:
Triple Analysis: Lung Cancer, Melanoma and Cancer Vaccines
Triple Analysis: Breast Cancer, Lymphoma and Melanoma
