This triple analysis focuses on cancer drug development strategies in one specific cancer indication (Colorectal Cancer), one mechanism/target/effect area (Protein Kinase Inhibitors) and one compound specific area (Peptides). Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.
Below is a short synopsis of each part included in this report:
Part I: Colorectal Cancer
The colorectal cancer report part comprises defined and up to date development strategies for 347 colorectal cancer drugs within the portfolio of 182 investigators, from Ceased to Marketed. This part extensively analyses their 210 identified drug targets, organized into 205 drug target strategies, and assesses them in eight different compound strategies in colorectal cancer.
This part is based on the following publication:
A Decision Support Tool for Optimizing The Colorectal Cancer Pipeline: From Research and Development to Market
Part II: Protein Kinase Inhibitors
The protein kinase report comprises defined and up to date development strategies for 409 protein kinase drugs (990 projects) within the portfolio of 160 investigators, from Ceased to Marketed. This report part extensively analyses 133 identified targets of protein kinase drugs, organized into 200 drug target strategies, and assesses them in 57 different cancer indications.
This part is based on the following publication:
Protein Kinase Therapeutics in Oncology - Where to Commercialize?
Part III: Peptides
The cancer peptide drug report part comprises defined and up to date development strategies for 152 peptide drugs in oncology within the portfolio of 104 companies world-wide, from Ceased to Marketed. The report extensively analyses their 123 identified drug targets, organized into 103 drug target strategies, and assesses them in 56 cancer indications.
This part is based on the following publication:
Commercializing Peptides in Cancer: The Faster Route to Consider Your Options and Position of Others
The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:
* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives
* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties
* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities
* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities
* Supporting development of integrative molecule, pathway and disease area strategies
* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment
This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.
Key Topics Covered:
Part I: Colorectal Cancer
5.1 The Scope of this Report 28
6 Consider the Therapeutic Target Among Colorectal Cancer Drugs for the Highest Therapeutic Outcome and Return on Investment (210 Drug Targets) 32-451
7 Emerging New Products to Established Ones: Drug Target Strategies of Colorectal Cancer Drugs by their Highest Stage of Development (205 Drug Target Strategies and 347 Colorectal Cancer Drugs) 452-699
8 Compound Strategies at Work: Competitive Benchmarking of Colorectal Cancer Drugs by Compound Strategy (8 Compound Strategies) 700-745
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Colorectal Cancer Drug Pipeline by Investigator (182 Companies) 746-1,039
10 Disclaimer 1040
11 Drug Index 1041
12 Company Index 1050
Figures: Includes 6 Figures
Tables: Includes 242 Tables
Total Number of Pages: 1,056
Part II: Protein Kinase Inhibitors
5.1 The Scope of this Report 30
6 Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (133 Drug Targets) 36-336
7 The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Profiles Identified in the Cancer Protein Kinase Therapeutic Pipeline? (200 Drug Target Strategies and 409 Drugs) 337-407
8 Compound Strategies at Work: Competitive Benchmarking of Protein Kinase Drugs in Oncology by Compound Type (7 Compound Strategies) 408-495
9 Selecting Cancer Indications for Protein Kinase Therapeutics (57 Different Cancer Indications) 496-649
10 Portfolio Planning: Competitive Benchmarking of Protein Kinase Cancer Therapeutic Pipeline by Investigator (160 Investigators) 650-1417
12 Drug Index 1419
13 Company Index 1433
Figures: Includes 6 Figures
Tables: Includes 302 Tables
Total Number of Pages: 1442
Part III: Peptides
5.1 The Scope of this Report 26
6 Consider the Therapeutic Target Among Peptide Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (123 Drug Targets) 30-248
7 Emerging New Products to Established Ones: Drug Target Strategies of Peptide Drugs in Oncology by their Highest Stage of Development (103 Drug Targets Strategies and 152 Peptide Drugs) 249-372
8 Selecting Indication for Peptide Drugs in Oncology (56 Cancer Indications) 373-441
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Peptide Drug Pipeline in Oncology by Investigator (104 Investigators and 152 Peptide Drugs) 442-895
10 Disclaimer 896
11 Drug Index 897
12 Company Index 902
Figures: Includes 5 Figures
Tables: Includes 207 Tables
Total Number of Pages: 906
4SC
7TM Pharma
Abbott
Abiogen
Abraxis BioScience
Acceleron Pharma
Adherex
Advenchen
AEgera
AEterna Zentaris
Affimed Therapeutics
Affymax
Aida Pharmaceuticals
Aileron Therapeutics
Alchemia
Alethia Biotherapeutics
Alfacell
Allos Therapeutics
Allostera
Allosterix
Alnylam
AlphaVax
Alseres Pharmaceuticals
Ambit Biosciences
Ambrilia Biopharma
Amgen
Amphora
Anavex Life Sciences
Anchor Therapeutics
AngioChem
Angstrom Pharmaceuticals
Antisense Pharma
AplaGen Biopharmaceuticals
ApopLogic Pharmaceuticals
Apotex
Apthera
Ardana
Ariad
Arno Therapeutics
ArQule
Array BioPharma
Astellas
Astex Therapeutics
AstraZeneca
Attenuon
AVEO
AVI BioPharma
Baxter International
Bayer
Benitec
Berkeley Lab
Betapharma
BioAlliance Pharma
BioAxone
Biocompatibles
Biogen Idec
Biokine Therapeutics
BioNumerik
Biotecnol
BioVex
Boehringer Ingelheim
Bristol-Myers Squibb
BTG
Callisto Pharmaceuticals
Can-Fite BioPharma
CanBas
Cancer Advances
Cancer Innovations
Cancer Research Technology
CDG Therapeutics
Celator Pharmaceuticals
Celecure
Celera
Celgene
Cell Therapeutics
Celldex Therapeutics
Cellmid
Celsion
Celtic Pharma
Center of Molecular Immunology
Cephalon
CG Therapeutics
ChemGenex Pharmaceuticals
Chemokine Therapeutics
Choongwae
Circadian Technologies
Clavis Pharma
Cleveland BioLabs
Clinuvel
CompleGen
Compugen
Cosmo Pharmaceuticals
CuraGen
Curaxis
CureTech
Curis
Cyclacel
Cylene Pharmaceuticals
Cynvec
CytImmune Sciences
Cytokinetics
Daiichi Sankyo
Dainippon Sumitomo Pharma
Deciphera Pharmaceuticals
Dendreon
DeveloGen
Diatos
Digna Biotech
Dongkook Pharm
Dyax
Dynavax Technologies
EGEN Inc
Eisai
Elara Pharmaceuticals
Eli Lilly
Endo Pharmaceuticals
Enkam Pharmaceuticals
EntreMed
Enzon
Epeius Biotechnologies
EpiCept
Esperance Pharmaceuticals
Etubics
Exelixis
FasTrack Pharmaceuticals
Galapagos
Galena Biopharma
Genentech
Generex
Genmab
GENova Biotherapeutics
Genovax
Genta
GenVec
Genzyme
Gilead Sciences
GlaxoSmithKline
Gliknik
GlycoGenesys
GP Pharm
Gradalis
Green Cross
Gryphon Therapeutics
Hanmi
Heidelberg Pharma
Hoffmann-La Roche
Human Genome Sciences
Idera Pharmaceuticals
IkerChem
ImClone Systems
ImmunoCellular Therapeutics
Immunocore
ImmunoFrontier
Immunomedics
Immunotope
ImmuPharma
Incyte Corporation
InNexus Biotechnology
Innovive
Inovio
Insmed
Insys Therapeutics
Introgen Therapeutics
Ipsen
ISA Pharmaceuticals
ISU ABXIS
Ivy Medical Chemicals
Jennerex Biotherapeutics
Johnson & Johnson
KAI Pharmaceuticals
Kalypsys
Karyon-CTT
Kiadis
Kirin Pharma
Kyowa Hakko Kirin
Labopharm
Lee’s Pharmaceutical
Leo
Locus Pharmaceuticals
Lorus Therapeutics
MacroGenics
Marillion Pharmaceuticals
MaxoCore Pharmaceuticals
MBiotec
Meda
MediGene
Mediolanum
Medisyn Technologies
Merck & Co
Merck KGaA
Merrimack
Mersana Therapeutics
MethylGene
Micromet
Mitsubishi Tanabe Pharma
MolMed
Mologen
Nektar Therapeutics
Nemod Biotherapeutics
NeoPharm
Nerviano Medical Sciences
Neurobiological Technologies
NicOx
Nidus Laboratories
NIH
Nippon Kayaku
Nippon Shinyaku
Non-industrial source
Novartis
Novogen
NPS Pharmaceuticals
Nycomed Pharma
Oncalis
OncoGenex Pharmaceuticals
OncoMed
Onconova
OncoTherapy Science
Oncothyreon
Oncozyme Pharma
Onyvax
Orca Therapeutics
Orchestra Therapeutics
OSI Pharmaceuticals
Oxford BioMedica
OXiGENE
PanaGin
Pepscan Therapeutics
Peptagen
PepTx
Peregrine Pharmaceuticals
Pfizer
Pharmaclon
Pharmacyclics
PharmaGap
PharmaMar
Pharmexa
Philogen
Pierre Fabre
Piramal
Plexxikon
POZEN
Pro-Pharmaceuticals
Protagonist
Protherics
Q Chip
QLT
Raptor Pharmaceutical
Reata Pharmaceuticals
Receptor BioLogix
Regeneron
Rexahn
Rigel
Sanofi-Aventis
Santaris Pharma
Sareum
SBIO
Scancell
Schering-Plough
SciClone Pharmaceuticals
Semafore Pharmaceuticals
Serometrix
Shire
Sigma-Tau
Silence Therapeutics
Simcere Pharmaceuticals
Soligenix
Spectrum Pharmaceuticals
Spirogen
SRI International
SuperGen
Supratek Pharma
Switch Pharma
SynDevRx
Synta Pharmaceuticals
Taiho
Takeda
Talon Therapeutics
Targa Therapeutics
TargeGen
Targepeutics
Tau Therapeutics
Taxolog
Tekmira Pharmaceuticals
Telik
Thallion Pharmaceuticals
The Genetics Company
Therion Biologics
Theryte
ThromboGenics
Tigris Pharmaceuticals
Titan Pharmaceuticals
ToolGen
TopoTarget
Transgene
Trion Pharma
UCB
Unigene
United Biomedical
VasGene Therapeutics
Vaxil BioTherapeutics
Vaxon Biotech
VaxOnco
Vertex Pharmaceuticals
Vical
Wilex
VioQuest Pharmaceuticals
Viralytics
ViroMed
Wyeth
Xencor
Xerion
Xigen
Yakult Honsha
YM BioSciences
Zelos Therapeutics
Zensun
A6
abarelix
ABT-510
AEZS-108
afamelanotide
aflibercept
alvocidib
angiopep+paclitaxel
Angiozyme
ARQ-197
axitinib
bevacizumab
BIBW-2992
brivanib alaninate
capecitabine
catumaxomab
CBP-501
cediranib
cetuximab
corticorelin acetate
dasatinib
deforolimus
deslorelin
doxifluridine
E-75
emepepimut-S
enzastaurin hydrochloride
erlotinib
everolimus
gefitinib
goserelin
GV-1001
GX-301
histrelin
idronoxil
imatinib mesilate
imMucin
interferon gamma
IPP-204106
irinotecan bead
irinotecan hydrochloride
ISA-P53-01
lapatinib ditosylate
lestaurtinib
leuprolide
leuprolide acetate
MDX-1379
MGN-1703
midostaurin
motesanib diphosphate
NAFB001
netupitant
nilotinib
OTS-102
ozarelix
panitumumab
pasireotide
pasireotide LAR
pazopanib hydrochloride
perifosine
raltitrexed
ramucirumab
regorafenib
rindopepimut
romurtide
sorafenib tosylate
sotatercept
sunitinib malate
tanespimycin
tegafur + uracil
tegafur + uracil + leucovorin
temsirolimus
thymalfasin
tigapotide triflutate
TM-30339
TS-1
vandetanib
VX-001
XL-184
Other selected research from the 'Triple Analysis' category:
Triple Analysis: Pancreatic Cancer, Apoptosis and Angiogenesis
Triple Analysis: Leukemia, Prostate Cancer and Protein Kinase Inhibitors
Other selected research from the 'Oncology' category:
Triple Analysis: Colorectal Cancer, Apoptosis and Antibodies
Triple Analysis: Lymphoma, Apoptosis and Antibodies
