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Triple Analysis: Leukemia, Prostate Cancer and Protein Kinase Inhibitors

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Published Date May 1, 2012
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Find the Triple Analysis Report in oncology which best suits your needs by selecting any three (3) out of these 14 high impact Cancer Focus Areas.

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Quick Overview

This triple analysis focuses on cancer drug development strategies in both Leukemia and Prostate Cancer and by the mechanism/target/effect of Protein Kinase Inhibitors.
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This triple analysis focuses on cancer drug development strategies in both Leukemia and Prostate Cancer and by the mechanism/target/effect of Protein Kinase Inhibitors. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.

Below is a short synopsis of each part included in this report:

Part I: Leukemia
The leukemia report part comprises defined and up to date development strategies for 313 leukemia drugs within the portfolio of 186 investigators, from Ceased to Marketed. This part extensively analyses their 204 identified drug targets, organized into 193 drug target strategies, and assesses them in eight different compound strategies and and eight subindications of leukemia.
This part is based on the following publication:
A Decision Support Tool for Optimizing The Leukemia Pipeline: From Research and Development to Market

Part II: Prostate Cancer
The prostate cancer report part comprises defined and up to date development strategies for 346 prostate cancer drugs within the portfolio of 198 investigators, from Ceased to Marketed. This report part extensively analyses 202 identified targets of prostate cancer drugs, organized into 187 drug target strategies, and assesses them in prostate cancer.
This part is based on the following publication:
A Decision Support Tool for Optimizing the Prostate Cancer Pipeline: From Research and Development to Market

Part III: Protein Kinase Inhibitors
The protein kinase drug report part comprises defined and up to date development strategies for 648 drugs in oncology within the portfolio of 212 companies world-wide, from Ceased to Marketed. The report extensively analyses their 183 identified drug targets, organized into 278 drug target strategies, and assesses them in 70 cancer indications.
This part is based on the following publication:
Competitive Insights to Protein Kinase Therapeutics in Oncology: The Faster Route to Consider Your Options and Position of Others

The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:

* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives

* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties

* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities

* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities

* Supporting development of integrative molecule, pathway and disease area strategies

* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment

This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.

Key Topics Covered:

Part I: Leukemia
5.1 The Scope of this Report 29
6 Consider the Therapeutic Target Among Leukemia Drugs for the Highest Therapeutic Outcome and Return on Investment (204 Drug Targets) 33-443
7 Emerging New Products to Established Ones: Drug Target Strategies of Leukemia Drugs by their Highest Stage of Development (193 Drug Target Strategies and 313 Leukemia Drugs) 444-727
8 Compound Strategies at Work: Competitive Benchmarking of Leukemia Drugs by Compound Strategy (8 Compound Strategies) 679-728
9 Selecting Subindication for Leukemia Drugs (8 Subindications of Leukemia) 729-762
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Leukemia Drug Pipeline by Investigator (186 Companies) 763-1,129
11 Disclaimer 1130
12 Drug Index 1131
13 Company Index 1140
Figures: Includes 6 Figures
Tables: Includes 253 Tables
Total Number of Pages: 1,147

Part II: Prostate Cancer
5.1 The Scope of this Report 28
6 Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (202 Drug Targets) 32-383
7 Emerging New Products to Established Ones: Drug Target Strategies by their Highest Stage of Development in the Prostate Cancer Pipeline (187 Drug Target Strategies and 346 Drugs) 384-438
8 Compound Strategies at Work: Competitive Benchmarking of Prostate Cancer Drugs by Compound Strategy (8 Different Compound Strategies) 439-485
9 Pipeline and Portfolio Planning: Competitive Benchmarking of Prostate Cancer Therapeutic Pipeline by Investigator (198 Investigators) 486-820
11 Drug Index 822
12 Company Index 831
Figures: Includes 6 Figures
Tables: Includes 257 Tables
Total Number of Pages: 838

Part III: Protein Kinase Inhibitors
5.1 The Scope of this Report 38
6 Consider the Therapeutic Target Among Protein Kinase Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (183 Drug Targets) 42-516
7 Emerging New Products to Established Ones: Drug Target Strategies of Protein Kinase Drugs in Oncology by their Highest Stage of Development (278 Drug Target Strategies and 648 Drugs) 517-945
8 Compound Strategies at Work: Competitive Benchmarking of Protein Kinase Cancer Drugs by Compound Strategy (8 Compound Strategies) 946-1013
9 Selecting Indication for Protein Kinase Drugs in Oncology (70 Cancer Indications) 1014-1223
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Protein Kinase Drug Pipeline in Oncology by Investigator (212 Investigators and 648 Drugs) 1224-2939
11 Disclaimer 2940
Figures: Includes 8 Figures
Tables: Includes 389 Tables
Total Number of Pages: 2,940

This Report Includes the Following Companies:
3M Pharmaceuticals
4SC
AB Science
Abbott
Abiogen
Abraxis BioScience
Acceleron Pharma
ACT Biotech
Actinium Pharmaceuticals
Active Biotech
Advantagene
Advaxis
Advenchen
AEgera
AEterna Zentaris
Agenus
Aida Pharmaceuticals
Alchemia
Alethia Biotherapeutics
Alexion
Alfa Wassermann
Allist Pharmaceuticals
Allos Therapeutics
Allostera
AlphaVax
Alseres Pharmaceuticals
Altor BioScience
Ambit Biosciences
Ambrilia Biopharma
Amgen
Amphora
Anavex Life Sciences
Ansaris
Antisense Pharma
Antisoma
Aphios
Apogee Biotechnology
ApopLogic Pharmaceuticals
Apotex
Apthera
Arca biopharma
Archer Biosciences
Ardana
Ariad
Arno Therapeutics
ArQule
Array BioPharma
Asahi Kasei Pharma
Ascenta Therapeutics
Astellas
Astex Pharmaceuticals
Astex Therapeutics
AstraZeneca
Attenuon
AVI BioPharma
Avila Therapeutics
Bavarian Nordic
Baxter International
Bayer
Bellicum Pharmaceuticals
Benitec
Berkeley Lab
Bio-Path Holdings
BioAxone
BioCryst Pharmaceuticals
Bioenvision
Biogen Idec
BioLineRx
Bionovo
BioSante
Biostar
Biotecnol
Biotica Technology
Bioton
Boehringer Ingelheim
Bristol-Myers Squibb
BTG
Cadila
Callisto Pharmaceuticals
Cambrex
CanBas
Cancer Research Technology
Catalyst Biosciences
Cel-Sci
Celator Pharmaceuticals
Celera
Celgene
Cell Genesys
Cell Therapeutics
CellCeutix
Celldex Therapeutics
Celleron
Celsion
Center of Molecular Immunology
Cephalon
CerRx
ChemGenex Pharmaceuticals
Chemokine Therapeutics
Choongwae
Chroma Therapeutics
Circadian Technologies
CJ Corp
Clavis Pharma
Cleveland BioLabs
Clinical Data
CompleGen
Compugen
CoNCERT Pharmaceuticals
Cornerstone Pharmaceuticals
CSL
Curacyte
CureTech
Curis
Cyclacel
Cylene Pharmaceuticals
CytImmune Sciences
Cytokine PharmaSciences
Cytokinetics
Cytopia
Daiichi Sankyo
Dainippon Sumitomo Pharma
Dara Biosciences
Debiopharm
Deciphera Pharmaceuticals
Dendreon
DeveloGen
DiaMedica
Dong-A
Dongkook Pharm
Dyax
ECI
Eisai
Elan
Elara Pharmaceuticals
Eleos
Eli Lilly
Emergent BioSolutions
Endo Pharmaceuticals
Endocyte
Enkam Pharmaceuticals
EntreMed
Enzon
EpiCept
Epizyme
Erimos
Esperance Pharmaceuticals
EUSA Pharma
Exelixis
ExonHit Therapeutics
Galapagos
Galena Biopharma
Gemin X Biotechnologies
Genencor
Genentech
Generex
Genmab
GENova Biotherapeutics
Genta
Genzyme
Gerolymatos
Geron
Gilead Sciences
GlaxoSmithKline
Gloucester Pharmaceuticals
GlycoGenesys
GlycoMimetics
Got-a-Gene
GP Pharm
GPC Biotech
Green Cross
Hanmi
Harbor BioSciences
Hayashibara
Heber Biotec
Hoffmann-La Roche
Human Genome Sciences
Hutchison China MediTech
Hypha Discovery
Idera Pharmaceuticals
IDM Pharma
IkerChem
ImClone Systems
Immune Pharmaceuticals
Immunocore
ImmunoFrontier
ImmunoGen
Immunomedics
Incozen Therapeutics
Incyte Corporation
InDex Pharmaceuticals
Inex
Infinity Pharmaceuticals
Inhibiton Therapeutics
Innate Pharma
Innovive
Inovio
Insmed
Insys Therapeutics
Intas Biopharmaceuticals
Intellikine
Introgen Therapeutics
Ipsen
Isis Pharmaceuticals
ISU ABXIS
Italfarmaco
Ivy Medical Chemicals
Jina Pharmaceuticals
Johnson & Johnson
Kadmon
KAI Pharmaceuticals
KaloBios
Kalypsys
Kanisa
Karus Therapeutics
Keryx Biopharmaceuticals
Kiadis
Kinex
Kirin Pharma
KuDOS
Kyowa Hakko Kirin
LEAD Therapeutics
Leo
Lexicon Pharmaceuticals
LFB Biotechnologies
LG Life Sciences
Ligand
Lorus Therapeutics
Mannkind
Marillion Pharmaceuticals
Marina Biotech
MAT Biopharma
MaxCyte
MaxoCore Pharmaceuticals
Meda
Medarex
MediGene
MedImmune
Mediolanum
Medisyn Technologies
Memgen
Menarini
Merck & Co
Merck KGaA
Merrimack
MethylGene
Micromet
Mitsubishi Tanabe Pharma
Mojave Therapeutics
Molecular LogiX
Mologen
Myrexis
Nano Terra
Nektar Therapeutics
NeoPharm
Nereus Pharmaceuticals
Nerviano Medical Sciences
NexusPharma
NicOx
Nidus Laboratories
NIH
Nippon Shinyaku
Non-industrial source
Northwest Biotherapeutics
Novacea
NovaLead
Novartis
Novogen
Oncalis
OncoGenex Pharmaceuticals
Onconova
OncoTherapy Science
Oncothyreon
Oncovir
Orion Pharma
OSI Pharmaceuticals
Otsuka
Oxford BioMedica
Paladin Labs
Pantarhei Bioscience
Pathway Therapeutics
Pepscan Therapeutics
Peregrine Pharmaceuticals
Pfizer
Pharmacyclics
PharmaGap
PharmaMar
Pharmexa
Phoenix Biotechnology
PHusis Therapeutics
Pieris
PIERIS Proteolab
Pierre Fabre
Piramal
PIramed
Portola Pharmaceuticals
Proacta
Prochon Biotech
Progen
Progenics Pharmaceuticals
ProMetic Life Sciences
ProNAi Therapeutics
ProStrakan
Protox Therapeutics
Provid
Q Chip
QLT
Quantum Pharmaceuticals
Ras Therapeutics
Reata Pharmaceuticals
Receptor BioLogix
Regeneron
Regulon
Reliance Life Sciences
Rexahn
Rigel
Samtheo Biopharma
Samyang
Sangamo BioSciences
Sanofi
Sanofi-Aventis
Santaris Pharma
Sareum
SBI Biotech
SBIO
Scancell
Schering-Plough
Seattle Genetics
Selvita
Semafore Pharmaceuticals
Sentinel Oncology
Sepal Pharma
Serometrix
Servier
SGX Pharmaceuticals
Shenogen
Shire
Sidus
Silence Therapeutics
Soligenix
Southern Research Institute
Spirogen
SRI International
Stemline Therapeutics
Sunesis
SuperGen
Supratek Pharma
Swedish Orphan Biovitrum
Switch Pharma
SymBio Pharmaceuticals
Symbiotec
Symphogen
Synageva BioPharma
Synta Pharmaceuticals
Syntrix
Takeda
Talon Therapeutics
Tamir Biotechnology
Targa Therapeutics
TargeGen
Tau Therapeutics
TauTaTis
TCD Pharma
TeGenero
Tekmira Pharmaceuticals
Telik
Teva
Thallion Pharmaceuticals
Therion Biologics
Theryte
Tigris Pharmaceuticals
Titan Pharmaceuticals
ToolGen
TopoTarget
Tragara Pharmaceuticals
Transgene
TransTech Pharma
Trion Pharma
UCB
Unigene
United Biomedical
Valeant
VasGene Therapeutics
Vaxon Biotech
Velacor Therapeutics
Vernalis
Vertex Pharmaceuticals
Wilex
Vion Pharmaceuticals
VioQuest
VioQuest Pharmaceuticals
Viralytics
ViroMed
ViroTarg
VM Discovery
Wyeth
XBiotech
Xcovery
Xencor
Xerion
Xoma
Yamasa Corporation
YM BioSciences
Zenyaku Kogyo
A Shortlist of Drugs Included are:
abarelix
abiraterone acetate
AC-480
AE-37
AF-802
afatinib
aflibercept
alemtuzumab
alvocidib
AMG-386
amonafide malate
amsacrine
Angiozyme
apatinib
AR-42
ARQ-197
AT-7519
AT-9283
axitinib
AZD-8055
AZD-8931
bafetinib
barasertib
bardoxolone methyl
belinostat
bevacizumab
BEZ-235
BGT-226
BI-811283
BIBF-1120
bicalutamide
bisantrene
BMS-690514
BMS-754807
BMS-777607
bosutinib
brivanib alaninate
buserelin
Cabozantinib
CAL-101
CBP-501
CC-223
cediranib
celecoxib
cladribine
clofarabine
crizotinib
CSF-GM
cytarabine ocfosfate
cytarabine, injectable
dacomitinib
danusertib
dasatinib
daunorubicin
DCVax-prostate
decitabine
degarelix
denosumab
deslorelin
dinaciclib
docetaxel
dovitinib lactate
dutasteride
E-75
elacytarabine
endoxifen
ENMD-2076
enocitabine
enzastaurin hydrochloride
erlotinib
estramustine phosphate sodium
ethinyl estradiol sulfonate
everolimus
flutamide
foretinib
fostamatinib disodium
gefitinib
gemtuzumab ozogamicin
goserelin
GSK-2118436
histamine dihydrochloride
histrelin
IC-83
icrucumab
idarubicin
idronoxil
imatinib mesilate
INCB-028060
INSM-18
interferon
interferon (alpha-N1)
interferon (alpha)
interferon (alpha2)
interferon (alpha2a)
interferon (alpha2b)
interferon (alpha2c)
interferon (gamma)
interferon alpha-2b
ipilimumab
JI-101
KD032
KX2-391
lapatinib ditosylate
lenvatinib
lestaurtinib
leukemia vaccine
leuprolide
linifanib
linsitinib
lumiliximab
LY-2090314
masitinib
MDV-3100
MGCD-265
midostaurin
mitoxantrone
MK-1775
MKC-1
MLN-8237
MM-111
motesanib diphosphate
MVA-BN Her-2 vaccine
nadroparin
neratinib
nilotinib
nilutamide
NPB-001-056
obinutuzumab
oblimersen sodium
ofatumumab
ON-01910
onartuzumab
OSI-027
OTS-102
P276-00
pazopanib hydrochloride
PD-0332991
pegdinetanib
peginterferon alfa-2b
pentostatin
perifosine
PHA-848125AC
plitidepsin
ponatinib
PX-866
quinacrine
quizartinib dihydrochloride
RAF-265
ramucirumab
razoxane
regorafenib
rhIFN-alpha
ridaforolimus
rilotumumab
rituximab
ruxolitinib
RX-0201-N
SCH-900776
seliciclib
sirolimus
sobuzoxane
sorafenib tosylate
ß-lapachone
SU-6668
sunitinib malate
talmapimod
tamibarotene
tandutinib
telatinib
temsirolimus
teniposide
terameprocol
tipifarnib
tivozanib
toremifene citrate
triciribine phosphate
triptorelin
triptorelin pamoate
vandetanib
varlitinib
vemurafenib
volasertib
vosaroxin
XL-147
XL-281
XL-413
XL-647
XL-765
zibotentan
zorubicin
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