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Triple Analysis: Lymphoma, Pancreatic Cancer and Protein Kinase Inhibitors

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Published Date Mar 23, 2010
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Find the Triple Analysis Report in oncology which best suits your needs by selecting any three (3) out of these 14 high impact Cancer Focus Areas.

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Quick Overview

This triple analysis focuses on cancer drug development strategies in both Lymphoma and Pancreatic Cancer and by the mechanism/target/effect of Protein Kinase Inhibitors.
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This triple analysis focuses on cancer drug development strategies in both Lymphoma and Pancreatic Cancer and by the mechanism/target/effect of Protein Kinase Inhibitors. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.

Below is a short synopsis of each part included in this report:

Part I: Lymphoma
The lymphoma report part includes defined and up to date development strategies for 176 lymphoma therapeutic drugs (>230 projects) within the portfolio of 106 investigators, from Ceased to Marketed. In total the report assesses five different sub-indications of lymphoma (B-cell lymphoma, Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, T-cell lymphoma and Lymphoma (general)). This report part extensively analyses 124 identified targets of lymphoma drugs, organized into 109 drug target strategies, and assesses them in lymphoma.
This part is based on the following publication:
Lymphoma Drug Development Strategies at Work - Define Your Competition

Part II: Pancreatic Cancer
The pancreatic cancer report part comprises defined and up to date development strategies for 213 pancreatic cancer drugs within the portfolio of 137 investigators, from Ceased to Marketed. This report part extensively analyses 171 identified targets of pancreatic cancer drugs, organized into 142 drug target profiles, and assesses them in pancreatic cancer.
This part is based on the following publication:
Portfolio Analytics in the Pancreatic Cancer Pipeline and Portfolio Planning - High Unmet Medical Need but Where to Target?

Part III: Protein Kinase Inhibitors
The protein kinase report comprises defined and up to date development strategies for 409 protein kinase drugs (990 projects) within the portfolio of 160 investigators, from Ceased to Marketed. This report part extensively analyses 133 identified targets of protein kinase drugs, organized into 200 drug target strategies, and assesses them in 57 different cancer indications.
This part is based on the following publication:
Protein Kinase Therapeutics in Oncology - Where to Commercialize?

The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:

* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives

* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties

* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities

* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities

* Supporting development of integrative molecule, pathway and disease area strategies

* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment

This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.

Key Topics Covered:

Part I: Lymphoma
5.1 The Scope of this Report 22
6 Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (124 Drug Targets) 26-250
7 The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Profiles Identified in the Lymphoma Pipeline? (109 Drug Target Strategies and 176 Drugs) 251-280
8 Compound Strategies at Work: Competitive Benchmarking of Lymphoma Pipeline by Type of Compound (6 Different Compound Strategies) 281-312
9 Selecting a Sub-Indication of Lymphoma for Drug Development 313-450
10 Portfolio Planning: Competitive Benchmarking of Lymphoma Pipeline by Investigator (106 Investigators) 351-524
12 Drug Index 526
13 Company Index 531
Figures: Includes 17 Figures
Tables: Includes 164 Tables
Total Number of Pages: 535

Part II: Pancreatic Cancer
5.1 The Scope of this Report 24
6 Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (171 Drug Targets) 28
7 The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Strategies Identified in the Pancreatic Cancer Therapeutic Pipeline? (142 Drug Target Strategies and 213 Drugs) 333
8 Compound Strategies at Work: Competitive Benchmarking of Pancreatic Cancer Drugs by Compound Strategy (8 Different Compound Strategies) 374
9 Pipeline and Portfolio Planning: Competitive Benchmarking of Pancreatic Cancer Therapeutic Pipeline by Investigator (137 Investigators) 408-599
11 Drug Index 601
12 Company Index 606
Figures: Includes 5 Figures
Tables: Includes 193 Tables
Total Number of Pages: 610

Part III: Protein Kinase Inhibitors
5.1 The Scope of this Report 30
6 Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (133 Drug Targets) 36-336
7 The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Profiles Identified in the Cancer Protein Kinase Therapeutic Pipeline? (200 Drug Target Strategies and 409 Drugs) 337-407
8 Compound Strategies at Work: Competitive Benchmarking of Protein Kinase Drugs in Oncology by Compound Type (7 Compound Strategies) 408-495
9 Selecting Cancer Indications for Protein Kinase Therapeutics (57 Different Cancer Indications) 496-649
10 Portfolio Planning: Competitive Benchmarking of Protein Kinase Cancer Therapeutic Pipeline by Investigator (160 Investigators) 650-1417
12 Drug Index 1419
13 Company Index 1433
Figures: Includes 6 Figures
Tables: Includes 302 Tables
Total Number of Pages: 1442

This Report Includes the Following Companies:
Abbott
Abiogen
Abraxis BioScience
Active Biotech
Adherex
Aduro BioTech
Advantagene
Advaxis
Advenchen
AEgera
Aeterna Zentaris
Aida Pharmaceuticals
Alethia Biotherapeutics
AlphaVax
Ambit Biosciences
Amgen
Amphora
Antigenics
Antisense Pharma
Apthera
Archer Biosciences
Ariad
Arno Therapeutics
ArQule
Array BioPharma
Astellas
Astex Therapeutics
AstraZeneca
Attenuon
AVI BioPharma
Bayer
BioAxone
Biogen Idec
Bionovo
BioNumerik
BioVex
Boehringer Ingelheim
Bristol-Myers Squibb
BTG
Callisto Pharmaceuticals
Cancer Research Technology
Celgene
Cell Genesys
Cell Therapeutics
Celldex Therapeutics
Celsion
Celtic Pharma
Center of Molecular Immunology
Cephalon
CG Therapeutics
CompleGen
Curis
Cyclacel
Cylene Pharmaceuticals
Cynvec
CytImmune Sciences
Cytokinetics
Daiichi Sankyo
Dainippon Sumitomo Pharma
Deciphera Pharmaceuticals
DeveloGen
Dyax
Dynavax Technologies
Eisai
Elan
Elara Pharmaceuticals
Eli Lilly
Enkam Pharmaceuticals
EntreMed
Enzon
Epeius Biotechnologies
EpiCept
Exelixis
Facet Biotech
Genentech
Generex
Genmab
Genta
GenVec
Genzyme
GlaxoSmithKline
Gloucester Pharmaceuticals
GlycoGenesys
Hana Biosciences
Hoffmann-La Roche
Human Genome Sciences
Hy BioPharma
Idera Pharmaceuticals
ImClone Systems
ImmunoCellular Therapeutics
ImmunoFrontier
Immunomedics
Immutep
Incyte Corporation
Inex
Innate Pharma
InNexus Biotechnology
Inovio
Insmed
Introgen Therapeutics
Ipsen
ISU ABXIS
Johnson & Johnson
KAI Pharmaceuticals
Kiadis
Kirin Pharma
Kyowa Hakko Kirin
Ligand
Locus Pharmaceuticals
Lorus Therapeutics
Meda
Medarex
MediGene
MedImmune
Merck & Co
Merck KGaA
MethylGene
Micromet
Nektar Therapeutics
NeoPharm
NicOx
Nidus Laboratories
NIH
Nippon Kayaku
Novartis
Novogen
Onconova
OncoTherapy Science
Oncothyreon
OSI Pharmaceuticals
Oxford BioMedica
OXiGENE
Paladin Labs
PanaGin
Pepscan Systems
Peregrine Pharmaceuticals
Pfizer
Pharmacyclics
PharmaEngine
PharmaGap
PharmaMar
Pharmexa
Pierre Fabre
Plexxikon
Pro-Pharmaceuticals
Reata Pharmaceuticals
Receptor BioLogix
Regeneron
Regulon
RESprotect
Rexahn
Rigel
Samyang
Sanofi-Aventis
Santaris Pharma
Sareum
Scancell
Schering-Plough
Seattle Genetics
Semafore Pharmaceuticals
Shire
SuperGen
Supratek Pharma
Switch Pharma
Taiho
Takeda
Targa Therapeutics
Tau Therapeutics
Telik
Thallion Pharmaceuticals
Therion Biologics
ToolGen
TopoTarget
Tragara Pharmaceuticals
Transgene
Trion Pharma
UCB
Vaccinex
VaxOnco
Vertex Pharmaceuticals
Wilex
Vion Pharmaceuticals
VioQuest
ViroMed
Wyeth
Xerion
Yakult Honsha
YM BioSciences
Zhejiang Beta Pharma
ZymoGenetics
A Shortlist of Drugs Included are:
131I-tositumomab
aflibercept
alvocidib
amrubicin hydrochloride
ARQ-197
axitinib
bevacizumab
bexarotene
BIBW-2992
bortezomib
brivanib alaninate
brivudine
capecitabine
catumaxomab
cediranib
cetuximab
dasatinib
deforolimus
denileukin diftitox
E-75
elliptinium acetate
enzastaurin hydrochloride
epirubicin
erlotinib
everolimus
forodesine hydrochloride
galiximab
gefitinib
golnerminogene pradenovec
GV-1001
HBP-347
ibritumomab tiuxetan
idronoxil
imatinib mesilate
inotuzumab ozogamicin
interferon
irinotecan hydrochloride
lapatinib ditosylate
larotaxel
lestaurtinib
masitinib
midostaurin
mitoxantrone
motesanib diphosphate
nadroparin
nilotinib
nimotuzumab
oblimersen sodium
ofatumumab
OTS-102
paclitaxel
pazopanib hydrochloride
pixantrone
ramucirumab
razoxane
rituximab
sobuzoxane
sorafenib tosylate
sunitinib malate
tanespimycin
tegafur + uracil
temsirolimus
teniposide
TS-1
vandetanib
XL-184
Request free sample pages from Triple Analysis: Lymphoma, Pancreatic Cancer and Protein Kinase Inhibitors

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