This triple analysis focuses on cancer drug development strategies in both Lymphoma and Prostate Cancer and by the mechanism/target/effect of Cancer Vaccines. Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.
Below is a short synopsis of each part included in this report:
Part I: Lymphoma
The lymphoma report part includes defined and up to date development strategies for 176 lymphoma therapeutic drugs (>230 projects) within the portfolio of 106 investigators, from Ceased to Marketed. In total the report assesses five different sub-indications of lymphoma (B-cell lymphoma, Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, T-cell lymphoma and Lymphoma (general)). This report part extensively analyses 124 identified targets of lymphoma drugs, organized into 109 drug target strategies, and assesses them in lymphoma.
This part is based on the following publication:
Lymphoma Drug Development Strategies at Work - Define Your Competition
Part II: Prostate Cancer
The prostate cancer report part comprises defined and up to date development strategies for 346 prostate cancer drugs within the portfolio of 198 investigators, from Ceased to Marketed. This report part extensively analyses 202 identified targets of prostate cancer drugs, organized into 187 drug target strategies, and assesses them in prostate cancer.
This part is based on the following publication:
A Decision Support Tool for Optimizing the Prostate Cancer Pipeline: From Research and Development to Market
Part III: Cancer Vaccines
The cancer vaccine report part comprises defined and up to date development strategies for 155 cancer vaccine drugs within the portfolio of 99 investigators, from Ceased to Marketed. This part extensively analyses their 94 identified drug targets, organized into 91 drug target strategies, and assesses them in 42 different cancer indications.
This part is based on the following publication:
Commercializing Cancer Vaccines: A Decision Support Tool for Optimizing the Pipeline
The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:
* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives
* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties
* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities
* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities
* Supporting development of integrative molecule, pathway and disease area strategies
* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment
This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.
Key Topics Covered:
Part I: Lymphoma
5.1 The Scope of this Report 22
6 Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (124 Drug Targets) 26-250
7 The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Profiles Identified in the Lymphoma Pipeline? (109 Drug Target Strategies and 176 Drugs) 251-280
8 Compound Strategies at Work: Competitive Benchmarking of Lymphoma Pipeline by Type of Compound (6 Different Compound Strategies) 281-312
9 Selecting a Sub-Indication of Lymphoma for Drug Development 313-450
10 Portfolio Planning: Competitive Benchmarking of Lymphoma Pipeline by Investigator (106 Investigators) 351-524
12 Drug Index 526
13 Company Index 531
Figures: Includes 17 Figures
Tables: Includes 164 Tables
Total Number of Pages: 535
Part II: Prostate Cancer
5.1 The Scope of this Report 28
6 Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment (202 Drug Targets) 32-383
7 Emerging New Products to Established Ones: Drug Target Strategies by their Highest Stage of Development in the Prostate Cancer Pipeline (187 Drug Target Strategies and 346 Drugs) 384-438
8 Compound Strategies at Work: Competitive Benchmarking of Prostate Cancer Drugs by Compound Strategy (8 Different Compound Strategies) 439-485
9 Pipeline and Portfolio Planning: Competitive Benchmarking of Prostate Cancer Therapeutic Pipeline by Investigator (198 Investigators) 486-820
11 Drug Index 822
12 Company Index 831
Figures: Includes 6 Figures
Tables: Includes 257 Tables
Total Number of Pages: 838
Part III: Cancer Vaccines
5.1 The Scope of this Report 26
6 Consider the Therapeutic Target Among Cancer Vaccine Drugs for the Highest Therapeutic Outcome and Return on Investment (94 Drug Targets) 30-194
7 Emerging New Products to Established Ones: Drug Target Strategies of Cancer Vaccine Drugs by their Highest Stage of Development (91 Drug Target Strategies and 155 Cancer Vaccine Drugs) 195-308
8 Compound Strategies at Work: Competitive Benchmarking of Cancer Vaccine Drugs by Compound Strategy (7 Compound Strategies) 309-338
9 Selecting Cancer Indications for Cancer Vaccine Drugs (42 Cancer Indications) 339-386
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Cancer Vaccine Drug Pipeline by Investigator (99 Investigators) 387-649
11 Disclaimer 650
12 Drug Index 651
13 Company Index 656
Figures: Includes 6 Figures
Tables: Includes 205 Tables
Total Number of Pages: 659
Abbott
Abiogen
Abraxis BioScience
AC Immune
Active Biotech
Adaptimmune
Aduro BioTech
Advantagene
Advaxis
AEgera
Aeterna Zentaris
Aida Pharmaceuticals
Akela Pharma
Alchemia
AlphaVax
Alseres Pharmaceuticals
Ambrilia Biopharma
Amgen
Antigenics
Antisense Pharma
Antisoma
Aphios
Apthera
Archer Biosciences
Ariad
ArQule
Array BioPharma
Astellas
AstraZeneca
Attenuon
AVI BioPharma
Bavarian Nordic
Bayer
Bellicum Pharmaceuticals
Biogen Idec
Biostar
BioVex
Boehringer Ingelheim
Bristol-Myers Squibb
BTG
Cadila
Cancer Research Technology
Cel-Sci
Cell Genesys
Cell Therapeutics
Celldex Therapeutics
Celsion
Center of Molecular Immunology
Cephalon
CG Therapeutics
ChemGenex Pharmaceuticals
Chemokine Therapeutics
Circadian Technologies
Cosmo Pharmaceuticals
CSL
Cyclacel
Cylene Pharmaceuticals
Cytokinetics
Daiichi Sankyo
Dainippon Sumitomo Pharma
Debiopharm
Dendreon
DeveloGen
Dongkook Pharm
Dynavax Technologies
ECI
Eisai
Elan
Eli Lilly
Endocyte
EntreMed
Enzon
Epeius Biotechnologies
EpiCept
Exelixis
Genentech
Generex
Genmab
GenOdyssee Pharmaceuticals
Genta
GENTICEL
Genzyme
Geron
GlaxoSmithKline
Gliknik
GlobeImmune
Gloucester Pharmaceuticals
GlycoGenesys
Got-a-Gene
Gradalis
Green Cross
Hoffmann-La Roche
Human Genome Sciences
Hy BioPharma
Ichor Medical Systems
Idera Pharmaceuticals
ImClone Systems
ImmunoCellular Therapeutics
Immunocore
ImmunoFrontier
ImmunoGen
Immunomedics
Immunotope
Incyte Corporation
Inex
Infinity Pharmaceuticals
Innate Pharma
InNexus Biotechnology
Inovio
Insmed
Introgen Therapeutics
Ipsen
ISA Pharmaceuticals
Isis Pharmaceuticals
Johnson & Johnson
Kyowa Hakko Kirin
LEAD Therapeutics
Ligand
Lorus Therapeutics
Marillion Pharmaceuticals
Meda
Medarex
Medical Marketing International
MediGene
MedImmune
Mediolanum
Menarini
Merck & Co
Merck KGaA
MethylGene
Micromet
MolMed
Mologen
Nektar Therapeutics
Nemod Biotherapeutics
NeoPharm
Neovacs
NIH
Northwest Biotherapeutics
Novartis
NovaRx
Novogen
OncoGenex Pharmaceuticals
OncoMune
OncoTherapy Science
Oncothyreon
Oncovir
Onyvax
Orion Pharma
OSI Pharmaceuticals
Oxford BioMedica
Paladin Labs
Pantarhei Bioscience
Pepscan Systems
Pepscan Therapeutics
Pfizer
Pharmacyclics
PharmaGap
PharmaMar
Pharmexa
Pierre Fabre
Prima Biomed
Progen
Progenics Pharmaceuticals
ProStrakan
Protherics
Protox Therapeutics
Radient Pharmaceuticals
Reata Pharmaceuticals
Receptor BioLogix
Regeneron
Regulon
responsif
Rexahn
Rigel
Samyang
Sanofi-Aventis
Santaris Pharma
Scancell
SciClone Pharmaceuticals
Seattle Genetics
Semafore Pharmaceuticals
Shire
SRI International
SuperGen
Supratek Pharma
Switch Pharma
Takeda
TapImmune
Tau Therapeutics
Telik
Thallion Pharmaceuticals
Therion Biologics
TopoTarget
Transgene
United Biomedical
Vaccinex
Vaxil BioTherapeutics
Vaxon Biotech
VaxOnco
Vectura
Vertex Pharmaceuticals
Vical
Wilex
Vion Pharmaceuticals
VioQuest
Viragen
Virionics
ViroMed
ViroTarg
Wyeth
Xerion
Xoma
Yakult Honsha
YM BioSciences
Zensun
ZymoGenetics
131I-tositumomab
abarelix
abiraterone acetate
ADXS11-001
AE-37
aflibercept
ALVAC-CEA/B7.1
amrubicin hydrochloride
astuprotimut-r
AVX-701
belagenpumatucel-L
bevacizumab
bexarotene
bicalutamide
bortezomib
BP-GMAX-CD1
buserelin
Cadi-05
CB-10-01
CEA-TRICOM
celecoxib
CG-201
CMLVAX-100
CTL901
CTP-37
CVac
dasatinib
DCVax-prostate
degarelix
denileukin diftitox
denosumab
deslorelin
docetaxel
dutasteride
E-75
elliptinium acetate
enzastaurin hydrochloride
epirubicin
estramustine phosphate sodium
ethinyl estradiol sulfonate
flutamide
forodesine hydrochloride
fowlpox-PSA vaccine
galiximab
goserelin
GRNVAC1
GV-1001
GV-1002
GVAX
GVX-3322
HBP-347
Her-2/Neu peptides
histrelin
ibritumomab tiuxetan
IGN-101
ImmunoVEX tri-melan
IMO-2055
INGN-225
inotuzumab ozogamicin
interferon
ipilimumab
irinotecan hydrochloride
leuprolide
MAGE-3-TK
MDV-3100
ME-103
MGN-1601
mitoxantrone
MSI vaccine
MVA-BN
MVA-BN Her-2 vaccine
nadroparin
nilutamide
Norelin
oblimersen sodium
ofatumumab
Onyvax-105
OTS-102
PANVAC-VF
pDOM-PSMA27
PEP-223
pixantrone
poly-ICLC
PR1:169-177 peptide
PROSTVAC
PX-104.1
razoxane
Reximmune-C
rindopepimut
rituximab
SAI-EGF
sobuzoxane
Stimuvax
sunitinib malate
temsirolimus
teniposide
TG-4001
TG-4010
thymalfasin
toremifene citrate
triptorelin
triptorelin pamoate
TroVax
verpasep caltespen
VX-001
zibotentan
ZYC-300
Other selected research from the 'Triple Analysis' category:
Triple Analysis: Melanoma, Prostate Cancer and Angiogenesis
Triple Analysis: Breast Cancer, Protein Kinase Inhibitors and Peptides
Other selected research from the 'Oncology' category:
Triple Analysis: Prostate Cancer, Angiogenesis and Protein Kinase Inhibitors
Triple Analysis: Breast Cancer, Prostate Cancer and Antibodies
