This triple analysis focuses on cancer drug development strategies in one specific cancer indication (Pancreatic Cancer), one mechanism/target/effect area (Apoptosis) and one compound specific area (Antibodies). Each of these three individual parts is evaluated according to standardized criteria in a five pillar pipeline drug assessment methodology to compare drug development strategies in oncology. This makes it easy to find and compare analysis not only within one single cancer focus area but also between different areas.
Below is a short synopsis of each part included in this report:
Part I: Pancreatic Cancer
The pancreatic cancer report part comprises defined and up to date development strategies for 247 pancreatic cancer drugs within the portfolio of 158 investigators, from Ceased to Marketed. This part extensively analyses their 197 identified drug targets, organized into 163 drug target strategies, and assesses them in eight different compound strategies.
This part is based on the following publication:
Commercializing Pancreatic Cancer Drugs: The Faster Route to Consider Your Options and Position of Others
Part II: Apoptosis
The apoptotic cancer drug report part comprises defined and up to date development strategies for 234 drugs in oncology within the portfolio of 158 companies world-wide, from Ceased to Marketed. The report extensively analyses their 181 identified drug targets, organized into 157 drug target strategies, and assesses them in 69 cancer indications.
This part is based on the following publication:
Commercializing Apoptotic Drugs in Cancer: The Faster Route to Consider Your Options and Position of Others
Part III: Antibodies
The cancer antibody drug report part comprises defined and up to date development strategies for 531 antibody drugs in oncology within the portfolio of 196 companies world-wide, from Ceased to Marketed. The report extensively analyses their 255 identified drug targets, organized into 266 drug target strategies, and assesses them in 75 cancer indications.
This part is based on the following publication:
The Global Competitive Landscape of Antibody Drug Development in Cancer: The Faster Route to Consider Your Options and Position of Others
The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It helps teams to maximize molecule value by selecting optimal development plans and manage risk and uncertainty. The report serves as an external commercial advocate for pharmaceutical companies’ pipeline and portfolio planning (PPP) in cancer by:
* Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives
* Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug’s properties
* Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities
* Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities
* Supporting development of integrative molecule, pathway and disease area strategies
* Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment
This report provides systems, analytical and strategic support both internally to PPP and to stakeholders across your own organization. The report will also be an important part of creating and implementing a market development plan for cancer drugs to insure that the optimal market conditions exist by the time the products are commercialized.
Key Topics Covered:
Part I: Pancreatic Cancer
5.1 The Scope of this Report 27
6 Consider the Therapeutic Target Among Pancreatic Cancer Drugs for the Highest Therapeutic Outcome and Return on Investment (197 Drug Targets) 31-422
7 Emerging New Products to Established Ones: Drug Target Strategies of Pancreatic Cancer Drugs by their Highest Stage of Development (163 Drug Target Strategies and 247 Drugs) 423-612
8 Compound Strategies at Work: Competitive Benchmarking of Pancreatic Cancer Drugs by Compound Strategy (8 Compound Strategies) 613-651
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Pancreatic Cancer Drug Pipeline by Investigator (158 Investigators and 247 Drugs) 652-1088
10 Drug Index 1091
11 Company Index 1098
Figures: Includes 7 Figures
Tables: Includes 218 Tables
Total Number of Pages: 1,103
Part II: Apoptosis
5.1 The Scope of this Report 33
6 Consider the Therapeutic Target Among Apoptotic Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (181 Drug Targets) 37-416
7 Emerging New Products to Established Ones: Drug Target Strategies of Apoptotic Drugs in Oncology by their Highest Stage of Development (157 Drug Target Strategies and 234 Drugs) 417-622
8 Compound Strategies at Work: Competitive Benchmarking of Apoptotic Cancer Drugs by Compound Strategy(7 Compound Strategies) 623-660
9 Selecting Indication for Apoptotic Drugs in Oncology (69 Cancer Indications) 661-776
10 Pipeline and Portfolio Planning: Competitive Benchmarking of the Apoptotic Drug Pipeline in Oncology by Investigator (158 Investigators and 234 Drugs) 777-1601
Disclaimer 1602
11 Drug Index 1603
12 Company Index 1611
Figures: Includes 7 Figures
Tables: Includes 315 Tables
Total Number of Pages: 1,617
Part III: Antibodies
5.1 The Scope of this Report 35
6 Consider the Therapeutic Target Among Antibody Drugs in Oncology for the Highest Therapeutic Outcome and Return on Investment (255 Drug Targets) 39-430
7 Emerging New Products to Established Ones: Drug Target Strategies of Antibody Drugs in Oncology by their Highest Stage of Development (266 Drug Targets Strategies and 531 Antibody Drugs) 431-768
8 Selecting Cancer Indication for Antibody Drugs (75 Cancer Indications) 769-893
9 Pipeline and Portfolio Planning: Competitive Benchmarking of the Antibody Drug Pipeline in Oncology by Investigator (196 Investigators and 531 Antibody Drugs) 894-1,916
10 Disclaimer 1917
11 Drug Index 1918
12 Company Index 1934
Figures: Includes 5 Figures
Tables: Includes 347 Tables
Total Number of Pages: 1,944
A&G Pharmaceutical
AB Science
Abbott
Abiogen
Ablynx
AC Immune
Acceleron Pharma
Access
Actinium Pharmaceuticals
Active Biotech
Adherex
Advanced Life Sciences
Advantagene
Advaxis
AEgera
AEterna Zentaris
Affibody
Affimed Therapeutics
Affitech
AGY Therapeutics
Aida Pharmaceuticals
Aileron Therapeutics
Alder Biopharmaceuticals
Alethia Biotherapeutics
Alexion
Alfacell
Algeta
Alnylam
ALSP
Altor BioScience
Ambrilia Biopharma
Amgen
Amorfix Life Sciences
Anadys Pharmaceuticals
Anaphore
Anavex Life Sciences
Antisense Pharma
Antisoma
Anza Therapeutics
Aphios
Apogee Biotechnology
Apogenix
ApopLogic Pharmaceuticals
Apotex
Apricus Biosciences
Arana Therapeutics
Arca biopharma
Ardea Biosciences
arGEN-X
Ariad
Arno Therapeutics
ArQule
Array BioPharma
Ascenta Therapeutics
Astellas
Astex Therapeutics
AstraZeneca
Attenuon
Avaxia
AVEO
AVI BioPharma
Avila Therapeutics
Basilea Pharmaceutica
Bayer
Berkeley Lab
Betapharma
BioAlliance Pharma
BioAxone
Biocad
Biocon
Biogen Idec
BioInvent
Biolex
BioLineRx
Biomas
Bionovo
BioNumerik
BioSante
Biosceptre
Biotecnol
Biotest
BioVex
Boehringer Ingelheim
Bristol-Myers Squibb
BTG
Calando Pharmaceuticals
Cancer Advances
Cancer Innovations
Cancer Research Technology
CDG Therapeutics
Celera
Celgene
Cell Therapeutics
Celldex Therapeutics
Celltrion
Celsion
Celtic Pharma
Center of Molecular Immunology
Cephalon
CG Therapeutics
ChemoCentryx
Chlorogen
Chroma Therapeutics
Circadian Technologies
Cleveland BioLabs
CombinatoRx
CompleGen
Cornerstone Pharmaceuticals
Coronado Biosciences
Critical Outcome Technologies
CritiTech
CSL
CuraGen
Curaxis
CureTech
Curis
Cyclacel
Cylene Pharmaceuticals
Cynvec
CytImmune Sciences
Cytochroma
Cytokinetics
CytRx
Daewoong
Daiichi Sankyo
Dainippon Sumitomo Pharma
Dara Biosciences
Dendreon
DeveloGen
DiaMedica
Dompe
Dr Reddy’s
Dyax
EGEN Inc
Eisai
Elan
Eleos
Eli Lilly
Emergent BioSolutions
EntreMed
Epeius Biotechnologies
EpiCept
Epitomics
Erimos
Esperance Pharmaceuticals
EUSA Pharma
Exelixis
Faron Pharmaceuticals
Favrille
Femta Pharmaceuticals
FibroGen
Five Prime Therapeutics
Fusion Antibodies
Galaxy Biotech
Galectin Therapeutics
GammaCan
Ganymed Pharmaceuticals
Gene Techno Science
Genencor
Genentech
Genmab
Genomic Systems
GenPat77
Genta
GenVec
Gerolymatos
Geron
Gilead Sciences
GlaxoSmithKline
Gliknik
GlycoGenesys
Glycotope
GPC Biotech
Green Cross
Harbor BioSciences
Hawthorn Pharmaceuticals
Hoffmann-La Roche
Human Genome Sciences
Idera Pharmaceuticals
IDM Pharma
ImClone Systems
IMED
Immune Pharmaceuticals
ImmunoCellular Therapeutics
ImmunoGen
Immunomedics
ImmuPharma
Immutep
Infinity Pharmaceuticals
Innate Pharma
InNexus Biotechnology
Innovive
Inovio
Insmed
Insys Therapeutics
Intracel
Intradigm
Introgen Therapeutics
Ipsen
ISA Pharmaceuticals
Isis Pharmaceuticals
ISU ABXIS
Johnson & Johnson
Kadmon
Kaketsuken
KaloBios
Kalypsys
Keryx Biopharmaceuticals
Kirin Pharma
Kissei
Kyowa Hakko Kirin
Kyto Biopharma
Leo
LFB Biotechnologies
LG Life Sciences
Ligand
Lorus Therapeutics
MacroGenics
MAT Biopharma
MBiotec
Meda
Medarex
MediGene
MedImmune
Medisyn Technologies
Menarini
Merck & Co
Merck KGaA
Merrimack
Mersana Therapeutics
MethylGene
Micromet
Mitsubishi Tanabe Pharma
Mycenax
Nektar Therapeutics
Neovacs
Nereus Pharmaceuticals
Nerviano Medical Sciences
Neuren
NIH
Nippon Kayaku
Nippon Shinyaku
NKT Therapeutics
Non-industrial source
Northwest Biotherapeutics
Novacea
NovaLead
Novartis
Novelix
Novogen
OncoMed
Onconova
OncoTherapy Science
Oncothyreon
Oncozyme Pharma
Onyvax
OSI Pharmaceuticals
Oxford BioMedica
OXiGENE
Paladin Labs
Panacea
PanaGin
PanGenetics
Patrys
Pepscan Therapeutics
Peregrine Pharmaceuticals
Perseus Proteomics
Pfizer
Pharmacyclics
PharmaMar
Pharmexa
Pharminox
Philogen
Pierre Fabre
Piramal
Prima Biomed
ProCell Therapeutics
Prochon Biotech
Progenics Pharmaceuticals
ProMetic Life Sciences
Protgen
QLT
Ramot
Ras Therapeutics
Reata Pharmaceuticals
Recepta biopharma
Receptor BioLogix
Regeneron
Regulon
RESprotect
Rexahn
Rigel
Rosetta Genomics
Rottapharm Madaus
Samyang
Sanofi
Sanofi-Aventis
Santaris Pharma
SBI Biotech
Scancell
Seattle Genetics
Semafore Pharmaceuticals
Senesco Technologies
Shenogen
Shire
Sigma-Tau
SRI International
Stainwei Biotech
Sunol Molecular
SuperGen
SuppreMol
Switch Pharma
SymBio Pharmaceuticals
Symbiotec
Symphogen
Synageva BioPharma
SynerGene Therapeutics
Taiho
Takeda
Talon Therapeutics
Tapestry Pharmaceuticals
Targa Therapeutics
Tau Therapeutics
Taxolog
TeGenero
Telik
TetraLogic Pharmaceuticals
Teva
Thallion Pharmaceuticals
Therapure Biopharma
Therion Biologics
ThromboGenics
Tigris Pharmaceuticals
Titan Pharmaceuticals
Tolerx
TopoTarget
Tracon Pharmaceuticals
Tragara Pharmaceuticals
Transgene
Trillium Therapeutics
Trion Pharma
UCB
UMN Pharma
United Therapeutics
Vaccinex
Wakunaga
ValiRx
VasGene Therapeutics
VaxOnco
VBL Therapeutics
Velacor Therapeutics
Vertex Pharmaceuticals
Vical
Wilex
Vion Pharmaceuticals
VioQuest
Viragen
Viralytics
ViroMed
ViroTarg
Viventia Biotech
VM Discovery
XBiotech
Xencor
Xerion
Xoma
Y’s Therapeutics
Yakult Honsha
YM BioSciences
Zenotech
Zeria
131I-tositumomab
abagovomab
AEG-35156
aflibercept
AGS-1C4D4
alemtuzumab
alvocidib
AME-133
AMG-386
APG-101
apricoxib
ARC-100
ARQ-197
AS-101
AS-1411
bardoxolone methyl
belinostat
bevacizumab
bortezomib
bosutinib
brentuximab vedotin
brivanib alaninate
brivudine
BZL-101
Cabozantinib
canfosfamide hydrochloride
capecitabine
catumaxomab
celecoxib
cenersen
cetuximab
CG-201
cilengitide
cintredekin besudotox
cixutumumab
conatumumab
CPI-613
CRLX-101
crolibulin
dalotuzumab
dasatinib
denosumab
dinaciclib
docetaxel
doxorubicin
dulanermin
E-7820
eniluracil
enzastaurin hydrochloride
erlotinib
everolimus
farletuzumab
fosbretabulin tromethamine
galiximab
ganitumab
gataparsen
gefitinib
gemtuzumab ozogamicin
girentuximab
GSK-1120212
GT-111
GV-1001
GVAX
HE-3235
ibritumomab tiuxetan
icotinib hydrochloride
idronoxil
imatinib mesilate
imetelstat
IMP-321
inotuzumab ozogamicin
ipilimumab
irinotecan
irinotecan hydrochloride
kahalalide F
KD032
L19-IL2
lapatinib ditosylate
lestaurtinib
LipoVIL12
litronesib
lonaprisan
lumiliximab
mapatumumab
masitinib
MetXia
MKC-1
mocetinostat
motexafin gadolinium
nadroparin
naptumomab estafenatox
navitoclax
necitumumab
nimotuzumab
noscapine
obinutuzumab
oblimersen sodium
ofatumumab
olaparib
ON-01910
Oncohist
oregovomab
OTS-102
P-276-00
paclitaxel
PancAtak
panitumumab
panobinostat
pasireotide
pasireotide LAR
PAT-SC1
pazopanib hydrochloride
PBI-1402
PCI-24781
PCI-27483
pemetrexed disodium
pentamidine isethionate
perifosine
pertuzumab
plitidepsin
PX-12
quarfloxacin
quinacrine
R-(-)-gossypol
RAF-265
ramucirumab
Reditux
retaspimycin
Rexin-G
rituximab
romidepsin
RX-0201
sagopilone
seliciclib
selumetinib
siltuximab
sorafenib tosylate
SPC-2996
ß-lapachone
SU-6668
sunitinib malate
talminogene laherparepvec
tegafur + uracil
temsirolimus
terameprocol
tigapotide triflutate
tigatuzumab
tipifarnib
TL-32711
tocilizumab
trabedersen
trastuzumab
triciribine phosphate
TRU-016
TS-1
tucotuzumab celmoleukin
varlitinib
vismodegib
volasertib
volociximab
vosaroxin
WX-671
XL-147
XL-647
Z-360
zalutumumab
zanolimumab
Other selected research from the 'Triple Analysis' category:
Triple Analysis: Leukemia, Melanoma and Peptides
Triple Analysis: Colorectal Cancer, Cancer Vaccines and Peptides
Other selected research from the 'Oncology' category:
Triple Analysis: Leukemia, Cancer Vaccines and Protein Kinase Inhibitors
Financial Markets Research: ASCO Review Part I - A summary of highlights presented at the ASCO 2006 Annual Meeting
